| Acronym | Meaning |
| VPF | Vertical Processing Facility |
| VRM | Venus Radar Mapper |
| VS | SNGVooruzhennikh Sil SNG |
| VTHL | Vertical Takeoff Horizontal Landing |
| VTVL | Vertical Takeoff Vertical Landing |
| VVS | Voenno-Vosdushniye Sili |
| WD | White Dwarf |
| WFF | Wallops Flight Facility |
| WFPC | Wide Field/Planetary Camera |
| WFPCII | Replacement For WFPC |
| WIMP | Weakly Interacting Massive Particle |
| WINDII | Wind Imaging Interferometer |
| WIYN | Wisconsin/Indiana/Yale/NOAO Telescope |
| WMO | World Meterological Organisation |
| WR | Western Range |
| WSGT | White Sands Ground Terminal |
| WSMR | White Sands Missile Range |
| WTR | Western Test Range |
| WUPPE | Wisconsin Ultraviolet PhotoPolarimter Experiment |
| XMM | X-ray Multi Mirror |
| XUV | Extreme Ultraviolet |
| YSC | Yokohama Science Center |
| YSO | Young Stellar Object |
| ZCG | Zeolite Crystal Growth |
| ZHR | Zenith Hourly Rate |