| Acronym | Meaning |
 | BRITE | Basic Research In Industrial Technologies Europe |
| BRL | Ballistics Research Laboratory |
| BRMS | Basin Rainfall Monitoring System |
| BRS | Bibliographic Retrieval Service |
| BSAC | Biotechnology Science Advisory Committee |
| BSD | Berkeley Software Distribution |
| BSD UNIX | Berkeley Software Distribution UNIX |
| BSDI | Berkeley Software Design |
| BSI | British Standards Institute |
| BSR | Budget Surplus Report |
| BSR | Bus Select Relay |
| BSRN | Boulder Science Resource Network |
| BSRN | Baseline Surface Radiation Network |
| BSTS | Boost Surveillance And Tracking System |
| BSU | Beam Steering Unit |
| BTAG | Biological Technical Assistance Group |
| BTU | British Thermal Unit |
| BU | Bargaining Unit |
| BUFR | Binary Universal Form For The Representation Of Meteorological Data |
| BUREC | Bureau Of Reclamation |
| BUS | Business Operations |
| BUV | Backscatter Ultraviolet |
| BV | Building Ventilation |
| BWC | Biological Weapons Convention |
| BWI | Baltimore-Washington International Airport |
| BWIP | Basalt Waste Isolation Project |
| BX | Base Exchange |
| BXA | Bureau Of Export Administration |
| C | A Programming Language Used Extensively In Systems Software |
| C&C | Consultation And Cooperation Agreement |
| C&DH | Command And Data Handling |
| C&DM | Configuration And Data Management |
| C++ | An Object-oriented Programming Language Based On C |
| C/D | Integrated Phase C And Phase D Contract |
| C2F3CL3 | CFC-113 |
| C2FBR2 | Halon 2402 |
| CA | Citizen Act |
| CAA | Clean Air Act |
| CAA | Concepts Analysis Agency |
| CAAA | Clean Air Act Amendments |
| CAAC | Civil Aviation Administration Of China |
| CAALS | Consortium On Automated Standards |
| CAAP | Composition And Acidity Of SE Asian Precipitation |
| CAB | CCSM Advisory Board |
| CABALS | Carrier Balloon System |
| CAC | Central Analysis Center (NMC) |
| CAC | Climate Analysis Center |
| CAC | California Administrative Code |
| CACGP | Commission On Atmospheric Chemistry And Global Pollution |
| CACM | Communications Of The ACM |
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