| Acronym | Meaning |
 | CACR | Commission On Air Chemistry And Radioactivity |
| CAD | Computer-Aided Design |
| CAD | Computer-Aided Dispatch |
| CAD | Control Alternate Delete (PC Keyboard Reset Sequence) |
| CAD | Coronary Artery Disease |
| CAD/CAM | Computer-design/computer-aided Manufacturing |
| CADD | Computer-Aided Design And Drafting |
| CADRE | Center For Analysis Of Dynamics Of Atmospheric Regions |
| CADRE | Center For Analysis Of The Dynamics Of Regional Ecosystems |
| CAE | Cooler |
| CAE | Computer Aided Engineering |
| CAENEX | Complex Atmospheric Energetics Experiment |
| CAFE | Corporate Average Fuel Economy |
| CAG | Carcinogen Assessment Group |
| CAG | Convective Airspace Guidance |
| CAG | Computing Advisory Group |
| CAGE | Continental Africa GATE Experiment |
| CAGEX | CERES/ARM/GEWEX Experiment |
| CAI | Computer-aided Instruction |
| CAI | Controlled Air Incinerator |
| CAL | Computer-aided Learning |
| CAL | Cray Assembly Language |
| CAL | Continental Air Lines |
| CAL/VAL | Calibration/Validation |
| CALCOMP | California Computer Products |
| CALCRUST | Consortium For Study Of The California Crust |
| CALLS | California Academia Libraries List Of Serials |
| CALS | Computer-aided Acquisition And Logistics Support |
| CALTECH | California Institute Of Technology |
| CALUTRON | California University Cyclotron |
| CAM | Computer Aided Machining |
| CAM | Cost Account Manager |
| CAM | Computer-aided Manufacturing |
| CAM | Constant Air Monitor |
| CAM | Cost Account Manager |
| CAMAC | Computer-automated Measurement And Control |
| CAMEX | Coastal AMOS (Experiment) |
| CAMP | Committee On Aeronautical Meteorological Problems |
| CAO | Central Aerological Observatory |
| CAOS | Center For Atmosphere/Ocean Studies |
| CAP | Civil Air Patrol |
| CAP | Corporate Affiliates Program |
| CAP | Cost Account Plan |
| CAP | CGD Advisory Panel |
| CAPE | Convection And Precipitation/Electrification Experiment |
| CAPE | Convective Available Potential Energy |
| CAPOS | Chemistry And Production Of Smoke |
| CAPP | Center For Applied Parallel Processing |
| CAPPPI | Citizen Ambassador Program Of People To People International |
| CAPS | Center For The Analysis And Prediction Of Storms |
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