| Acronym | Meaning |
 | EUROTRAC | European Experiment For Transporting And Transforming Environmentally Relevant Trace Construction In The Troposphere |
| EUV | Extreme Ultraviolet |
| EV | Earned Value |
| EVE | Equilibrium Vegetation Ecology |
| EWE | Equatorial Winds Experiment |
| EWF | Early Warning Form |
| EXABYTE | Boulder-based Computer Company |
| EXAMETNET | Experimental Inter-American Meteorological Rocket Network |
| EXCEL | Experimental Chloride Extraction Line |
| EXEC | Executable Program |
| EXOSAT | European X-ray Observatory Satellite |
| EXPRESSO | EXPeriment For REgional Sources And Sinks Of Oxidants |
| EXPRS | EXpendable Probe Receiver System |
| F | Fahrenheit |
| F | Femto |
| F | Frequency |
| F | Forad |
| F&A | Finance And Administration |
| F-V | Fussell-Vesely |
| F/P-INT | Fabry-Perot Interferometer |
| F/P-INT | Fabry Perot Interferometer |
| F77 | FORTRAN77 |
| FAA | Federal Aviation Administration |
| FAC | Facilities Advisory Council |
| FAC | Friday Afternoon Club |
| FACA | Federal Advisory Committee Act |
| FACE | Florida Area Cirrus Experiment |
| FACE | Also Known As FACE '75 |
| FAGS | Federation Of Astronomical And Geophysical Services |
| FAL | Frontier Airline |
| FAME | Florida Area Mesoscale Experiment |
| FAME | Formatting And Multiplexing Equipment |
| FAN | File Array Notation |
| FAO | Food And Agriculture Organization |
| FAPS | Fate Of Atmospheric Pollutants Study |
| FAPS | Freedom Attached Payloads |
| FAQ | Frequently Asked Questions |
| FAS | Federation Of American Scientists |
| FASB | Financial Accounting Standards Board |
| FASCODE | Fast Atmosphere Signature Code |
| FASE | Foundation For Advancement In Science And Education |
| FASINEX | Frontal Air-Sea Interaction Experiment |
| FASTEX | Fronts Atlantic Storm Track Experiment |
| FAT | Factory Acceptance Test |
| FATS | Factory Acceptance Test Specification |
| FATS | Firearms Training Simulator |
| FATS | FORTRAN Automatic Timing System |
| FATS | Forward Area Target Surveillance System |
| FATS | South African Air Force Tactical Support Command |
| FB | Blanketing Frequency |
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