| Acronym | Meaning |
 | ACS | Auxiliary Cooling System |
| ACSE | Association Control Service Element |
| ACSH | American Council On Science & Health |
| ACSYS | Arctic Climate System Study |
| ACT | Atmospheric Chemical Transformations |
| ACTS | Atmospheric Chemistry Of Transient Species |
| ACTS | Advanced Communications Technology Satellite |
| ACV | Air-cushion Vehicle |
| ACV | At-completion Variance |
| ACVC | Arms Control Verification Committee |
| ACWA | American Clean Water Association |
| ACWP | Actual Cost Of Work Performed |
| AD&D | Accidental Death And Dismemberment |
| ADA | Americans With Disabilities Act |
| ADA | Applied Decision Analysis |
| ADAAC | EOS Program |
| ADAACS | Affiliated Distributed Active Archive Centers |
| ADARS | Aircraft Data Acquisition And Recoding System |
| ADATS | Automated Data Acquisition And Transfer System |
| ADB | Apple Desktop Bus |
| ADC | Analog-to-digital Converter |
| ADC | Affiliated Data Center |
| ADC | Authorized Derivative Classifier |
| ADCLS | Advanced Data Collection And Location System |
| ADDE | Abstract Distributed Data Environment |
| ADDS | Aviation Digital Data Service |
| ADEOS | Advanced Earth Observing Satelite |
| ADEPT | Alexandria Digital Earth Prototype |
| ADF | Automatic Direction Finding |
| ADF | Advanced Development Facility |
| ADI | Acceptable Daily Intake |
| ADI | Alternating Direction Implicit |
| ADI | Air Defense Initiative |
| ADISS | Analytical Data Interchange And Storage Standards |
| ADL | Above Detection Limit |
| ADL | Alexandria Digital Library |
| ADM | Action Description Memorandum |
| ADM | Arrow Diagram Method |
| ADM | Atomic Demolition Munition |
| ADM | Administrative Services Section |
| ADMP | Acid Deposition Modeling Project |
| ADO | Associate Director For Operations |
| ADP | Administrative Data Processing |
| ADP | Automatic Data Processing |
| ADP | Anderson |
| ADPE | Automatic Data Processing Equipment Or ADP Equipment |
| ADR | Alternative Dispute Resolution |
| ADR | Audit Discrepancy Report |
| ADS | Activity Data Sheet |
| ADS | Airborne Data System |
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