| Acronym | Meaning |
| LANTEX | Lantau Experiment |
| LAOL | Los Alamos Opacity Library |
| LAPB | Local Analysis And Prediction Branch |
| LAPS | Local Analysis And Prediction System |
| LAPS | Local Area Prediction System |
| LARC | Langley Research Center |
| LARC | Limited Area Remote Collector |
| LAS | Laboratory Of Atmospheric Science |
| LAS | LAGEOS Apogee Stage |
| LASA | Lidar Atmospheric Sounder And Altimeter |
| LASERS | Learning About Science Easily And Readily |
| LASP | Laboratory For Atmospheric And Space Physics |
| LATAS | Laser True Airspeed System |
| LAWS | Laser Atmospheric Wind Sounder |
| LAWS | Low Altitude Wind Shear |
| LBA/TRMM | Large Scale Biosphere-Atmosphere Experiment In Amazonia/Tropical Rainfall Measuring Mission |
| LBJSC | Lydon B. Johnson Space Center |
| LBJSC | Lydon B Johnson Space Center |
| LBN | Lawrence Berkeley Laboratory |
| LC | Inductance-capacitance |
| LCC | Life Cycle Cost |
| LCD | Liquid Crystal Display |
| LCL | Lifting Consdensation Level |
| LCM | Large Core Memory |
| LDA | Local Data Acquisition |
| LDAD | Local Data Acquisition And Dissemination |
| LDAP | Lightweight Directory Access Protocol |
| LDM | Local Data Manager |
| LDN | Local Data Network |
| LDR | LIDAR |
| LDR | Linear Depolarization Ratio |
| LDS | Lightning Detection System |
| LDS | Linear Depolarization Ratio |
| LDS | Loral Defense Systems |
| LEADEX | Lead Experiment |
| LEARN | Laboratory Experience In Atmospheric Research |
| LEARN (PROJECT) | Laboratory Experience In Atmospheric Research |
| LED | Light Emitting Diode |
| LEDA | On-line Earthnet Data Access |
| LERC | Lewis Research Center |
| LES | Large-eddy Simulation |
| LEST | Large Earth-Based Solar Telescope |
| LEWEX | Labrador Extreme Waves Experiment |
| LF | Low Frequency |
| LFC | Large Format Camera |
| LFM | Limited-area Fine Mesh |
| LGSOWG | Landsat Ground Station Operators Working Group |
| LHS | Left-hand Side |
| LIDAR | Light Detection And Ranging Instrument |
| LIE | Line Islands Experiment |