| Acronym | Meaning |
| LSU | Louisiana State University |
| LSX | Land Surface Transfer Scheme |
| LT | Local Time |
| LTCS | Lower Thermosphere Coupling Study |
| LTE | Local Thermodynamic Equilibrium |
| LTER | Long Term Ecological Research |
| LTER | Long-Term Ecological Research Program |
| LTLOG | Landsat Technical Working Group |
| LTV | Ling-Temco-Vaught Inc. |
| LVBLE | Laramie Valley Boundary Layer Experiment |
| LVDT | Linear Variable Differential Transformer |
| LWC | Liquid Water Content |
| M | Mega |
| M | Mach |
| M | Milli |
| M&O | Maintenance And Operations |
| M&S | Materials And Services |
| M&V | Magnetism & Volcanoes |
| M&V | Magmatism & Volcanoes |
| M-ANL | Argonne National Laboratory |
| M-BNW | Batelle Northwest |
| M-ISWS | Illinois State Water Survey |
| M-PDU | Multiplexed Protocol Data Unit |
| M-SRI | Stanford Resource Institute |
| M-UCSD | University Of California At San Diego |
| M3 | M Cubed |
| MAB | Man And The Biosphere Program |
| MAB | Meteorological Applications Branch |
| MAC | Machine Aided Cognition |
| MAC | Multiple Access Computer |
| MAC | Manager's Advisory Council |
| MAC | Apple Macintosh Computer |
| MAC | Medium Access Control |
| MACCM2 | Middle Atmosphere Community Climate Model |
| MACCM3 | Middle Atmosphere Community Climate Model |
| MACRAT | Middle-Atmosphere Chemistry |
| MADAM | Master Data Acquisition Module |
| MADER | Management Of Atmospheric Data For Evaluation And Research |
| MADIS | Meteorological Assimilation Data Ingest System |
| MAF | Mesoscale Analysis Forecasting |
| MAG | Magnetosphere Currents/Fields |
| MAGE | Marine Aerosol And Gas Exchange Experiment |
| MAGE | Marine Gas Emissions |
| MAGSAT | Magnetic Field Satellite |
| MALTS | Marine Layer Thickness Study |
| MAMOS | Marine Automatic Meteorological Observing Station |
| MAMS | Multispectral Atmospheric Mapping Sensor |
| MAN | Metropolitan Area Network |
| MAP | Mesoscale Alpine Project |
| MAP | Metro-Agro-Plex |