| Acronym | Meaning |
| MNRAS | Monthly Notes Of The Royal Astronomical Society |
| MO&DSD | Mission Operations And Data Systems Directorate |
| MOA | Memorandum Of Agreement |
| MOA | Memorandum Of Agreement |
| MOBILHY | Modelisation Du Bilan Hydrique |
| MOCCA | Mobile Operations Center For Communication And Analysis |
| MOCD | Magneto-optics Compact Disk |
| MOD (+/OR DSI | Ministry Of Defense |
| MODAC | Meteorological Observation And Data Assimilation Center |
| MODCOMP | A Machine Manufactured By Modular Computer Systems Inc. |
| MODD | Meteorological And Omega Data Digitizer |
| MODE | Mid-Oceanic Dynamics Experiment |
| MODE | MODE In Cospar Papers |
| MODIS | Moderate Resolution Imaging Spectroradiometer |
| MODIS-T | Moderate Resolution Imaging Spectroradiometer-Tilt |
| MODS | Mission Operations And Data Systems |
| MOE | Measure Of Effectiveness |
| MOL | Manned Orbital Laboratory |
| MOLAS | Mono Lake APIPS Study |
| MOM | MASnet Operations Monitor |
| MOM | Mission Operations Manager |
| MONEX | Monsoon Experiment |
| MONTBLEX | Monsoon Trough Boundary Layer Experiment |
| MOPITT | Measurements Of Pollution In The Troposphere |
| MOPS | Millions Of Operations (106) Per Second |
| MOS | Model Output Statistics |
| MOS | Marine Observation Satellite |
| MOS | Metal-oxide Semiconductor |
| MOSES | Manned Open Sea Experiment Station |
| MOSES | Meteorological Observing Station |
| MOTIF | N/A |
| MOU | Memorandum Of Understanding |
| MOVIE.BYU | Colored Movie Software Produced By Brigham Young University |
| MOZART | Model For Ozone And Related Chemical Tracers |
| MP | Melting Point |
| MP | Mono-processing |
| MP | MASnet Code For The Xerox 4050 Laser Printers |
| MPA | Maintenance Purchase Award |
| MPC | Mother-of-pearl Clouds |
| MPD | Magnetospheric Particles Detectors |
| MPDATA | Multidimensional Positive Definite Advection Algorithm |
| MPI | Max Planck Institute |
| MPI | Message Passing Interface |
| MPIF | Message Passing Interface Forum |
| MPOA | Multi-Protocol Over ATM |
| MPP | Massively Parallel Processor |
| MPR | Advanced Microwave Precipitation Radiometer |
| MPS | Radar System |
| MPS | Mesoscale Prediction Section |
| MR | Management Reserve |