| Acronym | Meaning |
| AIRS | Advanced Inertial Reference Sphere |
| AIS | Airborne Imaging Spectrometer |
| AIS | Acceptable Intake For Subchronic Exposure |
| AIS | Accumulator Injection System |
| AIS | Administrative Information Systems |
| AIS | Affiliate Information System |
| AIS | Advanced Isotope Separation |
| AIS | Affiliate And Immigration Services |
| AISC | Assessment And Information Services Center |
| AISC | Industry |
| AISEC | Army Information Engineering Command |
| AIST | Agency Of Industrial Science & Technology |
| AIT | Audit Inventory Team |
| AIV | Aviation-impact Variable |
| AIX | Advanced Interactive Executive |
| AKP | Atmospheric Kinetics Project |
| AL | Aeronomy Laboratory |
| AL | Ames Laboratory |
| AL | Analytical Laboratory |
| AL | Authorized Leave With Pay |
| AL | Albuquerque Field Office |
| AL-WDD | Albuquerque Operations |
| AL/APD | ALO Advance Planning Division |
| AL/EPD | AL Environmental Protection Division |
| AL/FPMD | AL Facilities Planning & Maintenance Division |
| AL/HPD | AL Health Protection Division |
| AL/KAO | AL Kirtland Area Office |
| AL/MRD | AL Management Review Division |
| AL/OESH | AL Office Of Environment |
| AL/OIEA | AL Office Of Intergovernmental And External Affairs |
| AL/OQD | AL Operation Safety Division |
| AL/PIRD | AL Personnel |
| AL/SPD | AL Special Programs Division |
| AL/WMOSD | AL Waste Management & Operational Surety Division |
| ALA-O | Delta-aminolevulinic Acid Dehydrates |
| ALADIN | Atmospheric Laser Doppler Instrument |
| ALAP | As Low As Possible |
| ALAP | As Low As Practical |
| ALAPCO | Association Of Local Air Pollution Control Officials |
| ALARA | As Low As Reasonably Achievable |
| ALBM | Air-launched Ballistic Missile |
| ALBURT | Albuquerque Budget Reform Task |
| ALC | Airlift Circulator |
| ALC | Allocations |
| ALCLAD | Clad Aluminum Alloy |
| ALCM | Air-launched Cruise Missile |
| ALDEN | Alden Electronics |
| ALDF | Animal Legal Defense Fund |
| ALE | Atmospheric Lifetimes Experiment |
| ALE | Arbitrary Lagrangian-Eulerian |