| Acronym | Meaning |
 | USCG | United States Coast Guard |
| USDA | United States Department Of Agriculture |
| USDC | United States Department Of Commerce |
| USDI | United States Department Of Interior |
| USERC | United States Environmental And Resources Council |
| USFS | United States Forest Service |
| USGCRP | United States Global Change Research Program |
| USGS | United States Geological Survey |
| USIC | UCAR Space Implementation Committee |
| USJGOFS | United States Joint Global Ocean Flux Study |
| USN | United States Navy |
| USPHS | United States Public Health Service |
| USRA | Universities Space Research Association |
| USSDM | Unidata System For Scientific Data Management |
| USTAR | UCAR Scientist's Technical Areas Of Research |
| USWRP | United States Weather Research Program |
| UT | Universal Time |
| UT / LS | Upper Troposphere/ Lower Stratosphere |
| UTC | Universal Time Coordinate Or Coordinated Universal Time |
| UTC | United Technology Center |
| UUCP | UNIX-to-UNIX Copy |
| UUI | Uniform User Interface |
| UV | Ultraviolet |
| UV | UNAVCO Building |
| UVDM | Ultraviolet Double Monochromator |
| UVSP | Ultra-violet Spectrometer/polarimeter |
| UWGB | University Of Wisconsin At Green Bay |
| UWI | Uniform Window Interface |
| UWIS | University Of Wisconsin At Green Bay |
| VAD | Velocity-azimuth Display |
| VAFB | Vandenberg Air Force Base |
| VAI | High Positive Vorticity |
| VAP | Voluntary Assistance Program |
| VAS | VISSR Atmospheric Sounder |
| VBNS | Very High Performance Backbone Network Service |
| VCO | Voltage-controlled Oscillation |
| VELORT | Very Long Range Tracking |
| VEMAP | Vegetation And Ecosystem Modeling And Analysis Project |
| VF | Voice Frequency |
| VF | Voice Frequency |
| VG | Visualization Group |
| VHF | Very High Frequency |
| VHF | Very High Frequency |
| VHRR | Very High Resolution Radiometer |
| VHS | Video-Home System |
| VIL | Vertical Integrated Liquid |
| VIMHEX | Venezuela International Meteorological And Hydrological Experiments |
| VIP | Versatile Information Processing |
| VIRGS | VISSR Image Registration And Gridding System |
| VIS-UV | Visible/ultraviolet Spectrometer |
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