| Acronym | Meaning |
 | MICR | Magnetic Ink Character Recognition (Reader) |
| MIDI | Musical Instrument Digital Interface |
| MIF | Management Information Format |
| MILNET | Military Network |
| MIME | Multipurpose Internet Mail Extension |
| MIPS | Millions Of Instructions Per Second |
| MIS | Management Information System |
| MIS | Management Information Services |
| MLC | Multilevel Cell |
| MMDS | Multichannel Multipoint Distribution System |
| MMU | Memory Management Unit |
| MMX | Matrix Math Extensions (Multimedia Extensions) |
| MNG | Multiple-image Network Graphics |
| MNP | Microcom Networking Protocol |
| MODEM | Modulator/Demodulator |
| MOF | Meta Object Facility |
| MOO | Mud, Object Oriented |
| MOS | Metal Oxide Semiconductor |
| MOSFET | Metal Oxide Semiconductor Field Effect Transistor |
| MOSIS | MOS Implementation System |
| MOSS | Mime Object Security Services |
| MP3 | MPEG Layer 3 |
| MPC | Matchbox PC |
| MPC | Multimedia Personal Computer |
| MPEG | Motion Picture Experts Group |
| MPI | Message Passing Interface |
| MRC | Magneto-Resistive Cluster |
| MS-DOS | Microsoft Disk Operating System |
| MSN | Microsoft Network |
| MTA | Media Terminal Adapter |
| MTBF | Mean Time Between Failure |
| MTU | Maximum Transmission Unit |
| MUD | Multiple User (or Multi-User) Dungeon (Dimension) |
| MUSH | Multi-User Shared Hallucination |
| MVS | Multiple Virtual Storage |
| NAP | Network Access Point |
| NAS | Network-Attached Storage |
| NAT | Network Address Translation |
| NCSA | National Center For Supercomputing Applications |
| NDIS | Network Driver Interface Specification |
| NDMP | Network Data Management Protocol |
| NDS | Novell Directory Services |
| NETBEUI | Network BIOS Extended User Interface |
| NETBIOS | Network Basic Input Output System |
| NFS | Network File System |
| NGI | Next Generation Internet |
| NIC | Network Interface Card |
| NIMH | Nickel Metal Hydride |
| NNTP | Network News Transfer Protocol |
| NOP | No Operation |
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