| Acronym | Meaning |
 | NOS | Network Operating System |
| NSAPI | Netscape Server API |
| NSF | National Science Foundation |
| NSFNET | National Science Foundation Network |
| NSP | Network Service Provider |
| NTFS | NT File System |
| NTSC | National Television Standards Committee |
| NUMA | Non-Uniform Memory Access |
| NURBS | Non-Uniform Rational B-Spline |
| NVRAM | Non-Volatile RAM |
| OC | Optical Carrier |
| OCR | Optical Character Recognition |
| OCX | OLE Custom Control |
| ODBC | Open Database Connectivity |
| ODI | Open Data-link Interface |
| OEM | Original Equipment Manufacturer |
| OIM | Open Information Model |
| OLAP | Online Analytical Processing |
| OLE | Object Linking And Embedding |
| OLED | Organic Light-Emitting Diode |
| OLTP | On-Line Transaction Processing |
| OMG | Object Management Group |
| OMG | Oh My God |
| OOP | Object-Oriented Programming |
| OPENSRS | Open Shared Registration System |
| OPSEC | Open Platform For Secure Enterprise Connectivity Alliance |
| OSF | Open Software Foundation |
| OSI | Open System Interconnection |
| OSPF | Open Shortest Path First |
| OSR | OEM System Release |
| OTOH | On The Other Hand |
| P-SRAM | Pseudo-Static RAM |
| P3P | Platform For Privacy Preferences |
| PAD | Portable Application Description |
| PAL | Phase Alternating Line |
| PAL | Programmable Array Logic |
| PAN | Personal Area Network |
| PAP | Password Authentication Protocol |
| PB SRAM | Pipelined Burst Static RAM |
| PBX | Private Branch Exchange |
| PC | Personal Computer |
| PC/TV | Personal Computer And Television |
| PCB | Printed Circuit Board |
| PCI | Peripheral Component Interface |
| PCL | Printer Control Language |
| PCM | Pulse Code Modulation |
| PCMCIA | Personal Computer Memory Card International Association |
| PCS | Personal Communications System |
| PDA | Personal Digital Assistant |
| PDC | Primary Domain Controller |
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