| Acronym | Meaning |
| FDHD | Floppy Drive, High Density |
| FDM | Frequency Division Multiplexing |
| FF | Form Feed |
| FFS | Flash File System |
| FIF | Fractal Image Format |
| FIFO | First In, First Out |
| FLOPS | Floating-point Operations Per Second |
| FORTRAN | Formula Translator; Programming Language |
| FPM RAM | Fast Page Mode RAM |
| FPU | Floating-Point Unit |
| FR | Frame Relay |
| FRAD | Frame Relay Assembler/Disassembler |
| FRAM | Ferroelectric RAM |
| FSK | Frequency Shift Keying |
| FSP | File Service Protocol |
| FTP | File Transfer Protocol |
| FWIW | For What It's Worth |
| FYI | For Your Information |
| GBE | Gigabit Ethernet |
| GDI | Graphics Device Interface |
| GIF | Graphical Interchange Format |
| GIGO | Garbage In, Garbage Out |
| GIMP | General (GNU) Image Manipulation Program |
| GIS | Geographic Information System |
| GM | General MIDI |
| GMT | Greenwich Mean Time |
| GNU | Recursive Acronym For ?GNU's Not Unix? |
| GPF | General Protection Fault |
| GPRS | General Packet Radio Service |
| GPS | Global Positioning Satellite (System) |
| GREP | Globally Search For The Regular Expression And Print |
| GREP | Generalized Regular Expression Pattern-matcher |
| GRINS | Graphical Interface To SMIL |
| GSM | Global System For Mobiles |
| GUI | Graphical User Interface |
| GUID | Globally Unique Identifier |
| HAL | Hardware Abstraction Layer |
| HD | High Density |
| HD | Hard Drive |
| HDD | Hard Disk Drive |
| HDLC | High-level Data Link Control |
| HDML | Handheld Device Markup Language |
| HDR | High Data Rate |
| HDTV | High-Definition Television |
| HFS | Hierarchical Filing System |
| HMA | High Memory Area |
| HMD | Head-Mounted Display |
| HP | Hewlett-Packard |
| HP-GL | Hewlett-Packard Graphics Language |
| HPAS | Hypermedia Presentation And Authoring System |