| Acronym | Meaning |
| P-P | Peak-to-Peak (Value) |
| P-TUBE | Pneumatic Tube |
| P/A | Problem Analysis |
| P/B | Preburner |
| P/B | Pushbutton |
| P/C | Pitch Control |
| P/L | Parts List |
| P/L | Payload |
| P/L | Postlanding |
| P/L | Purchased Labor |
| P/N | Part Number |
| P/P | Patch Panel |
| P/P | Printer/Plotter |
| P/PL | Primary Payload |
| P/S | Parallel To Serial Converters |
| P/S | Payload Specialist |
| P/Y | Pitch/Yaw |
| PA | Pad Abort |
| PA | Paging And Area Warning |
| PA | Power Amplifier |
| PA | Product Assurance |
| PA | Public Address |
| PA | Public Affairs |
| PA | Pulse AmPlifier |
| PAC | Pressure Alpha Center |
| PAC | Probe Aerodynamic Center |
| PAC | Problem Action Center |
| PACAS | Personnel Access Control Accountability System |
| PACC | Problem Action Control Center |
| PACE | Prelaunch Automatic Checkout Equipment |
| PACS | Pointing And Attitude Control System |
| PAD | Preliminary Advisory Data (Crew Data Uplink) |
| PAD | ProgramApprovalDocument |
| PAD | Propellant Acquisition Device |
| PAE | Preventive Action Engineer |
| PAE | Problem Assessment Engineer |
| PAF | Payload Attach Fitting |
| PAF | Payload Attach Fitting |
| PAF | Peak Annual Funding |
| PAFB | Patrick Air Force Base |
| PAH | PaYload Accommodations Handbook |
| PAL | APA Indonesian Communications Satellite |
| PALS | Photo Area And Location SYstem |
| PALS | Precision Approach And Landing SYstem |
| PAM | Payload Assist Module |
| PAM | Payload Assist Module |
| PAM | Pulse Amplifier Modulation |
| PAM | Pulse Amplitude Modulation |
| PAM-A | PAM |
| PAM-D | PAM |