| Acronym | Meaning |
| PCN | Program Control Number |
| PCN | Program Change Notice |
| PCO | Postcheckout |
| PCO | Postcheckout Operations |
| PCO | Procuring Contracting Officer |
| PCO | Program Controlled Output |
| PCOT | Payload Center Operations Team |
| PCP | Power Control Panel |
| PCP | Program Change Proposal |
| PCP | Project Change Proposal |
| PCP | Project Cost Plan |
| PCR | Payload Changeout Room |
| PCR | Payload CheckoutRoom |
| PCR | Payload Changeout Room |
| PCR | Power Change Request |
| PCR | Program Change Request |
| PCR | Project Control Room |
| PCR | Publication Change Request |
| PCRB | Operations) |
| PCRB | Program Change Review Board (RI Launch |
| PCS | Payload Checkout System |
| PCS | Payload Control Supervisor |
| PCS | Pointing Control System |
| PCS | Power Conversion System |
| PCS | Pressure Control System |
| PCS | Primary Coolant System |
| PCS | Procedure Completion Sheet |
| PCT | Percent |
| PCTE | Portable Commercial Test Equipment |
| PCTO | Payload Cost Tradeoff Optimization |
| PCTR | Pad Connection Terminal Room |
| PCU | Payload Checkout Unit |
| PCU | Power Control Unit |
| PCU | Pressure Control Unit |
| PCU | Process Control Unit |
| PCV | Precheck Verification |
| PCV | Purge Control Valve |
| PCVB | Pyro Continuity Verification Box |
| PCVL | Pilot Controlled Visual Landing |
| PCZ | Physical Control Zone |
| PD | Pitch Down |
| PD | Preliminary Design |
| PD | Procurement Document |
| PD | Procurement Drawing |
| PD | Program Directive |
| PD | Project Directive |
| PD | Propellant Dispersal |
| PD&RS | Payload Deployment And Retrieval Subsystem |
| PDA | Propellant Drain Area |
| PDAR | Program Description And Requirements |