| Acronym | Meaning |
| PSC | Program Schedule Chart |
| PSCL | Propellant Systems Cleaning Laboratory |
| PSCN | Preliminary Specification Change Notice |
| PSD | Power SpectralDensity |
| PSD | Program Support Document |
| PSD | RPlanning And Scheduling Document Record |
| PSDP | Payload Station Distribution Panel |
| PSE | Payload Service Equipment |
| PSE | Payload Servicing Equipment |
| PSE | Payload Support Equipment |
| PSE | Peculiar Support Equipment |
| PSF | Pounds Per Square Foot |
| PSF | Processing And Staging Facility (SRB) |
| PSF | Processing And Storage Facility (ET) |
| PSFC | Power Supply/Fuel Cell |
| PSG | Power Subsystem Group |
| PSI | Pounds Per Square Inch |
| PSI | Pounds Per Square Inch (Static Pressure) |
| PSI | Power Static Inverter |
| PSIA | Pound Per Square Inch Absolute |
| PSIA | Pounds Per Square Inch Absolute |
| PSID | Pounds Per Square Inch Differential |
| PSID | Pounds Per Square Inch Differential |
| PSIG | Pounds Per Square Inch Gage |
| PSIG | Pounds Per Square Inch Gauge |
| PSIG | Propulsion Systems Integration Group |
| PSIS | Pounds Per Square Inch Sealed |
| PSK | Phase Shift Keyed |
| PSL | Pressure Seal |
| PSL | Propellant Seal |
| PSM | Phase Sensitive Modulator |
| PSM | Propellant Storage Module |
| PSM | Pyro Substitute Monitor |
| PSOP | Payload Systems Operating Procedures |
| PSP | Payload Signal Processor |
| PSP | Payload Signal Processor |
| PSP | Payload Specialist Panel |
| PSP | Payload Support Plan |
| PSP | Program Support Plan |
| PSP | Project Schedule Plan |
| PSPA | Pressure Static Probe Assembly |
| PSPL | Priced Spare Parts List |
| PSR | Program Status Review |
| PSRD | Program Support Requirements Document |
| PSS | Pad Safety Supervisor |
| PSS | Payload Specialist Station |
| PSS | Payload Support System |
| PSS | Propellant Supply Subsystem |
| PSS | Propulsion Support System |
| PSSP | Payload Specialist Station Panel |