| Acronym | Meaning |
| PSST | Periodic Significant Scheduled Tasks |
| PSSU | Patch Survey And Switching Unit |
| PSU | Power Switching Unit |
| PSV | Planetary Space Vehicle |
| PSW | Program Status Word |
| PT | Advanced Planning And Technology Office (KSC Dir.) |
| PT | Pint |
| PT | Pitch Trim |
| PT | Point |
| PT | Pressure Transducer |
| PTA | Positest Analysis |
| PTA | Potential Toxic Area |
| PTA | Propulsion Test Article |
| PTB | Payload Timing Buffer |
| PTC | Passive Thermal Control |
| PTC | Passive Thermal Control |
| PTC | Portable Temperature Controller |
| PTC | RPad Terminal Connection Room |
| PTCS | Planning |
| PTCS | Passive Thermal Control Section |
| PTCS | Passive Thermal Control System |
| PTCS | Propellant Tanking Computer System |
| PTD | Provisioning Technical Documentation |
| PTDDSS | PTD Data Selection Sheet |
| PTI | Preliminary Test Information |
| PTI | Programmed Test Input |
| PTIS | Program Test Input System |
| PTM | Pulse Time Modulation |
| PTMS | Precision Torque Measuring System |
| PTO | Participating Test Organizations |
| PTO | Power Test Operations |
| PTP | Point-to-Point Phone(s) |
| PTR | Preliminary Test Report |
| PTR | Printer |
| PTR | Program Trouble Report |
| PTS | Payload Test Set |
| PTS | Payload Transportation System |
| PTT | Push To Talk |
| PTT | Push-to-Talk |
| PTV | Pathfinder Test Vehicle |
| PU | Pickup |
| PU | Power Unit |
| PU | Propellant Unit |
| PU | Propellant Utilization |
| PUB | Publication |
| PUCS | Propellant Utilization Control System |
| PUGS | Propellant Utilization And Gaging System |
| PUPO | Pull Up Push Over |
| PUSS | Pallet Utility Support Structure |
| PUV | Propellant Utilization Valve |