| Acronym | Meaning |
| RQMTS | Requirements |
| RR | Range Rate |
| RR | RendezvousRadar |
| RR | Requirements Review |
| RR | Respiration Rate |
| RREA | Rendezvous Radar Electronics Assembly |
| RREU | Rendezvous Radar Electronics Unit |
| RRI | Rendezvous Radar Indicator |
| RRL | Rudder Reference Line |
| RRP | Rudder Reference Plane |
| RRT | Rendezvous Radar Transducer |
| RRT | Rendezvous Radar Transponder |
| RS | Rawinsonde |
| RS | Redundancy Status |
| RS | Redundant Set |
| RS | Redundant Set (computers) |
| RS | Refurbishment Spare |
| RS | Remote Station |
| RS | Right Side |
| RS&H | Reynolds |
| RS&S | Receiving |
| RSA | Reference Satellite A |
| RSB | RudderSpeedBrake |
| RSC | Range Safety Control/Command |
| RSCIE | Remote Station Communication Interface Equipment |
| RSD | Requirements And Specifications Document |
| RSDP | Remote Site Data Processor |
| RSF | Receiving-Safing Facility |
| RSF | Refurbishment And Subassembly Facilities |
| RSF | Refurbishment And Subassembly Facility (KSC) |
| RSI | Reusable Surface Insulation |
| RSL | Resource Support List |
| RSLV | Resolve |
| RSM | Resume |
| RSMM | Redundant System Monitor Model |
| RSO | Radiological Safety Office |
| RSO | Range Safety Officer |
| RSP | Rendezvous Station Panel |
| RSPL | Recommended Spare Parts List |
| RSS | Range SafetySwitch |
| RSS | Range SafetySystem |
| RSS | Range Safety System |
| RSS | Reactants Supply System |
| RSS | Rib Structure Station |
| RSS | Root Sum Square |
| RSS | Rotating Service Structure |
| RSS | Rotating Service Structure |
| RSSPO | Resident Space Shuttle Project Office (Officer) |
| RST | Recessed Selectromatic Terminal |
| RSTRT | Restart |