| Acronym | Meaning |
 | TBA | To Be Added |
| TBA | To Be Announced |
| TBC | Terminal Buffer Controller |
| TBD | To Be Defined |
| TBD | To Be Determined |
| TBD | To Be Developed |
| TBE | To Be Evaluated |
| TBF | Test De Bon Fonctionnement (Spacelab) |
| TBI | Through-Bulkhead Initiator |
| TBN | To Be Negotiated |
| TBP | To Be Provided |
| TBS | Task Breakdown Structure |
| TBS | To Be Specified |
| TBS | To Be Superseded |
| TC | Telecommunications |
| TC | Temperature Compensating |
| TC | Test Conductor (Contractor) |
| TC | Test Conductor (Controller) |
| TC | Thermal Control |
| TC | Thermocouple |
| TC | Thiokol Corporation |
| TC | Thrust Chamber |
| TC | Time To Circular |
| TC | Traceability Code |
| TC | Tracking Camera |
| TCA | Thrust Chamber Assembly |
| TCA | Time Of Closest Approach |
| TCA | Translation Controller Assembly |
| TCAB | Temperature Of Cabin |
| TCC | Test Control Center |
| TCC | Thermal Control Coating |
| TCD | Test Completion Date |
| TCD | Test Control Document |
| TCE | Thermal Canister Experiment |
| TCF | Tank Checkout Facility |
| TCG | Test Control Group |
| TCG | Time Code Generator |
| TCI | Technical Critical Item |
| TCID | Test Configuration Identifier Document |
| TCMD | Transportation Control And Movement Document |
| TCN | Test Change Notice |
| TCN | Transportation Control Number |
| TCO | Taken Care Of |
| TCO | Test And Checkout |
| TCOP | Test Checkout Pian(s) |
| TCP | Task Control Packet |
| TCP | Test Checkout Procedure |
| TCP | Test Control Package |
| TCP | Thrust Chamber Pressure |
| TCR | Test Compare Results |
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