| Acronym | Meaning |
| DPP | D'isposit'lon Record |
| DPP | Door |
| DPP | Drive |
| DPP | E)eve@opment-Right |
| DPS | Data Processing System |
| DPT | Design Proof Test |
| DPY | Deploy |
| DR | Dead Reckoning |
| DRA | Data Release Authorization |
| DRB | Design Requirements Baseline |
| DRB | Design Review Board |
| DRC | Data Reduction Center |
| DRC | Discrete Rate Command |
| DRD | Data Requirement Description |
| DRD | Data Requirements Document |
| DRD | DetailedRequirementsDocument |
| DRD | Document Requirement Description |
| DRF | Digital |
| DRF | Data RequestForm |
| DRF | DocumentationRequisitionForm |
| DRG | Digital Ranging Generator |
| DRI | Data Rate Indicator |
| DRIRU | Dry Rotor Inertial Reference Unit |
| DRK | Display Request Keyboard |
| DRL | Data Requirements List |
| DRL | Document Requirements List |
| DRM | Data Records Management |
| DRM | Design Reference Mission |
| DRM | Drawing Requirements Manual |
| DRN | Drain |
| DRO | Document Release Order |
| DROG | Drogue |
| DRR | Data Recorder/Reproducer |
| DRR | Design Requirements Review |
| DRS | Data Relay Satellite |
| DRS | Data Relay Station |
| DRS | Digital Range Safety |
| DRSS | Discrepancy Report SquawkSheet |
| DRT | Design Reference Timeline |
| DRUC | Disposition Record Unsatisfactory Condition |
| DS | Data Storage |
| DS& | R Data Storage And Retrieval |
| DSA | Defense Supply Agency |
| DSAD | Data Systems And Analysis Directorate (JSC) |
| DSB | Document Status Bulletin |
| DSB | Double Side Band |
| DSC | Data Separator Card |
| DSC | Dedicated Signal Conditioner |
| DSN | Deep-Space Network |
| DTP | Detail Test Plan |