| Acronym | Meaning |
| ECLSS | Environmental Control And Life Support System |
| ECLSS | Environmental Control And Life Support System |
| ECN | Engineering Change Notice |
| ECO | Engine Combustion |
| ECO | Engine Cutoff |
| ECO | Engineering Change Order |
| ECOS | Experiment Computer Operating System |
| ECP | Engineering Change Program |
| ECP | Engineering Change Proposal |
| ECP | Engineering Control Proposal |
| ECP | Explicitly Coded Program |
| ECR | Engineering Change Request |
| ECRA | Engineering Change Request/Authorization |
| ECS | Engine Control SYstem |
| ECS | Environmental Control System (Subsystem) |
| ECU | Electrical Control Unit |
| ECU | Electronic Coupling Unit |
| ECU | Environmental Control Unit |
| ED | Edge Distance |
| ED | Edit |
| ED | Engineering Directive |
| ED | Explosive Device |
| EDA | Electronic DisPlay Assembly |
| EDA | Elevation Drive Assembly |
| EDB | Environmental Data Book |
| EDC | Engineering Design Change |
| EDC(M) | Electrochemical DePolarized CO (Module) |
| EDCP | Engineering Design Change ProPosal |
| EDDR | Electron DiPole-DiPole Reservoir |
| EDF | Engineering Data File |
| EDLN | Engineering DeveloPment Logic Network |
| EDP | Electonic Data Processing |
| EDPE | Electronic Data Processing EquiPment |
| EDPM | Electronic Data Processing Machine |
| EDR | Engineering Design Review |
| EDS | Electrical Distribution System |
| EDS | Emergency Detection System |
| EDT | Eastern Daylight Time |
| EDT | Explosive Device System |
| EDU | Engineering DeveloPment Unit |
| EDV | Electronic Depressurizing Valve |
| EDW | Edwards Air Force Base |
| EDW | Edwards (TACAN Station) |
| EE | End Effector |
| EECOM | EleCtrical |
| EECOM | Electrical |
| EECOM | Systems (MPSR) |
| EED | Electro (Electrical) Explosive Device |
| EED | Electroexplosive Device |
| EEE | Electronic |