| Acronym | Meaning |
| EIS | End Item Specification |
| EIS | Environmental Impact Statement |
| EIS | Extended Instruction Set |
| EIT | Entry Interface Time |
| EIU | Engine Interface Unit |
| EIU | Engine Interface Unit |
| EIVT | Electrical And Instrumentation Verification Test |
| EIVT | Electrical Interface Verification Test |
| EIVT | Electronic Installation Verification Test |
| EJN | Ejection |
| EKG | Electrocardiogram (Record) |
| EKG | Electrocardiograph (Instrument) |
| EL | Elastic Limit |
| EL | Electroluminescent |
| EL | Electromagnetic Interference |
| EL | Electronic Interface |
| EL | Elevate |
| EL | Elevation Angle |
| EL | End Item |
| EL | Engineering Instruction |
| EL | Entry Interface |
| EL | Environmental Impact |
| EL | MECH Electromechanical |
| ELB | Elbow |
| ELDISC | Electrical Disconnect |
| ELDV | Electrically Operated Depressurization Valve |
| ELEC | Electric |
| ELEC | Electronic |
| ELECT | Electrical |
| ELECTR | Electronics |
| ELEV | Elevon |
| ELF | Extremely Low Frequency (1 Hz To 3 KHz) |
| ELINT | Electromagnetic Intelligence |
| ELMCH | Electromechanical |
| ELMS | Elastic Loop Mobility System |
| ELMS | Elements |
| ELS | Earth Landing System (Subsystem) |
| ELS | Eastern Launch Site |
| ELS | Elevon Load System |
| ELT | Emergency Locator Transmitter |
| ELV | Earth Launch Vehicle |
| ELV | Electrically Operated Valve |
| ELV | Expendable Launch Vehicle |
| ELVN | Eleven |
| EM | Emergency |
| EM | Engineering Model |
| EM | Exception Monitor |
| EMA | Electromagnetic Analysis |
| EMC | Electromagnetic Compatibility |
| EMCC | Emergency Mission Control Center |