| Acronym | Meaning |
| EMCD | Electro-Mechanical Control Diagram |
| EMCI | Engineering Model Configuration Inspection |
| EMD | Entry Monitor Display |
| EMEC | Electromagnetic Effects Capability |
| EMEC | Electromagnetic Effects Compatibility |
| EMER | Emergency |
| EMES | Electriral |
| EMF | Electromagnetic Force |
| EMF | Electromotive Force |
| EMG | Electromyograph(gram) |
| EMG | Surface Electromyograms |
| EMI | Electromagnetic Interference |
| EMIS | Emission |
| EMK | Emergency Medical Kit |
| EMK | Emergency Medical Kit |
| EML | Electromagnetic Laboratory |
| EMN | Engineering Management Network |
| EMON | ExceptionMonitoring |
| EMP | Electromagnetic Pulse |
| EMP | EquiPment Mounting Plate |
| EMPGS | Electrical/Mechanical Power Generation SubsYstem |
| EMR | Engine Mixture Ratio |
| EMRL | Equipment Maintenance Requirements List |
| EMS | Electromagnetic Susceptibility |
| EMS | Engineering Master Schedule |
| EMS | Entry Monitor Subsystem |
| EMS | Entry Monitoring System |
| EMSS | Electromagnetic Servoactuator SYstem |
| EMT | Electro-Mechanical Test |
| EMU | Engineering Model Unit |
| EMU | Extended Memory Unit |
| EMU | Extravehicular Mobility Unit |
| EMU | Extravehicular Mobility Unit |
| EMU-TV | Extravehicular MobilitY Unit - Television |
| ENA | Enable |
| ENC | Encode |
| ENCD | Encode |
| ENCL | Enclose |
| END | EFF End Effector |
| ENDF | Evaluated Neutron Data File |
| ENG | Engine |
| ENG | ElectronYstagnogram |
| ENGR | Engineer |
| ENGRG | Engineering |
| ENT | Entry |
| ENVIR | Environment |
| EO | Earth Observation |
| EO | Earth Orbit |
| EOC | End Of Contract |
| EOC | Engine Order Capability |