| Acronym | Meaning |
 | FS | Functional Schematic |
| FS | Fuselage Station |
| FSAA | Flight Simulator For Advanced Aircraft |
| FSC | Federal Stock Classification |
| FSCM | Federal Supply Code For Manufacturers |
| FSCP | Fire Sensor Control Panel |
| FSD | Flight Simulation Division (JSC) |
| FSD | Full Scale Development |
| FSE | Flight Simulation Engineer |
| FSF | First Static Firing |
| FSGS | Flare/Shallow Glide Slope |
| FSI | Final Systems Installation |
| FSIM | Functional Simulator |
| FSIWG | Flight System Interface Working Group |
| FSK | Frequency Shift Keyed (Keying) |
| FSL | Flight Systems Laboratory |
| FSL | Flight Simulation Laboratory |
| FSLO | First Spacelab Payload |
| FSLT | First Sea Level Test |
| FSM | Fuel Supply Module |
| FSN | Federal Stock Number |
| FSO | Functional Supplementary Objective |
| FSOH | Flight Support Operations Handbook |
| FSP | Fault Summary Page |
| FSR | Final System Release |
| FSR | Flight Specific Requirements |
| FSRR | Flight Software Readiness Review |
| FSRR | Flight System Readiness Review |
| FSRS | Flight System Recording System |
| FSS | Field Spectrometer System |
| FSS | Fire Suppression System |
| FSS | Fixed Service Structure |
| FSS | Fixed Service Structure |
| FSS | Flight Support Station (for MMU) |
| FSS | Flight Support Structure |
| FSS | Flight Support System |
| FSS | Flight Systems Simulator |
| FSSR | Flight Systems Software Requirements |
| FSSR | Functional Subsystem Software Requirements |
| FSTE | Factory Special Test Equipment |
| FSU | Freon Servicing Unit |
| FSW | Flight Software |
| FT | Feet |
| FT | Flight Team |
| FT | Flight Test |
| FT | Formal Training |
| FT | Functional Test |
| FT&C | Formal Training And Certification |
| FT/SEC | Feet Per Second |
| FTA | Fatigue Test Article |
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