| Acronym | Meaning |
| HSD | HoriZontal Situation Display |
| HSDL | High Speed Data Line |
| HSF | Hypergot Servicing Facility |
| HSG | High Sustained Gs Acceleration |
| HSI | Horizontal Situation Indicator |
| HSI | Horizontal Situation Indicator |
| HSK | Horizontal Sling Kit |
| HSL | Hardware Simulation Laboratory |
| HSNG | Housing |
| HSP | Health Stabilization Program |
| HSP | High Speed Printer |
| HSR | Hardware Status Register |
| HSS | High Speed Reader |
| HSS | High Stress Strain |
| HSS | Hydraulic Subsystem Simulator |
| HSTP | Hard Stop |
| HSU | Helium Service Unit |
| HT | Heat Transfer |
| HT | Height |
| HT | High Technology |
| HTC | Hybrid Technol Ogy ComPuter |
| HTEXCH | Heat Exchanger |
| HTG | Heating |
| HTLL | High Test Level Language |
| HTM | High Temperature |
| HTPB | Hydroxyl Terminated Polybutadiene (Propellant) |
| HTR | Heater |
| HTR | HydroxYl Terminated Polybutyiene |
| HTS | Heat Transfer System |
| HTS | Heat Transport Section |
| HUD | Head Up Display |
| HUD | Head-up Display |
| HUDE | Head Up Display Electronics |
| HUL | Hardware Utilization List |
| HUM | Humidity |
| HUT | Hard Upper Torso |
| HV | High Velocity |
| HV | High Voltage |
| HV | Hydrogen Vent |
| HVAC | Heating, Ventilating, Air-conditioning |
| HVDS | Hypergolic Vapor Detection System |
| HVPS | High Voltage Power Supply |
| HVR | Hover |
| HVSF | Honeywelf Verification Simulation Facility |
| HVSL | Holidays |
| HW | Ha Rd Wa Re |
| HW | Headwind |
| HW | Hotwire |
| HW/SW | Hardware/Software |
| HWWS | Hyperfiltration Wash Water Recovery System |