| Acronym | Meaning |
| IUS | Inertial UPper Stage (was Interim UPper Stage) |
| IUS | Interim Use Sheet |
| IUS | Interim/intermediate UPper State |
| IUS | International Ultraviolet ExPlorer |
| IV | Initial Velocity |
| IV | Integrated Vehicle |
| IV | Interface Volume |
| IV | Interior Upper Stage |
| IV | Intravehicular |
| IVA | Intravehicular Activity |
| IVA | Intravehicular Activity |
| IVAR | Internal Variable |
| IVBC | Integrated Vehicle Baseline Config |
| IVC | Intervehicular Communications |
| IVE | Interface Verification EquiPr-nent |
| IVL | Lntervatometer |
| IVSI | Instantaneous Vertical Speed Indicator |
| IVT | Intervehicular Transfer |
| IWBS | Indirect Work Breakdown Structure |
| IWG | Interface Working Group |
| IWG | Investigator Working Group |
| J/M | Jettison Motor |
| JAEIC | Joint Atomic Energy Intelligence Committee |
| JAN | Joint Army-Navy |
| JAS | Journal Of Aerospace Science |
| JB | Junction Box |
| JCL | Job Control Language |
| JCP | Joint Power Conditions |
| JCT | Junction |
| JED | Julian Ephemeris Data |
| JETS | Joint Electronics Type (Designation) System |
| JETT | Jettison |
| JIR | Job Improvement Request |
| JO | Job Order |
| JOD | Joint Occupancy Data |
| JOD | Joint Occupancy Date |
| JOIP | Joint Operations Interface Procedure |
| JOP | Joint Operating Procedure |
| JOP | Jupiter Orbiter Probe-Galilee |
| JOR | Job Order Request |
| JOULE | (SI UJoule (SI Unit) |
| JOVIAL | Joules Own Version International Algebraic Language |
| JP | Jet Propellant |
| JP | Jet Propulsion |
| JPC | Joint Power Condition |
| JPIC | Joint Program Integration Committee |
| JPL | Jet Propulsion Laboratory |
| JPL | Jet Propulsion Laboratory |
| JPOC | JSC Payload Operations Center |
| JPP | Joint Program Plan |