| Acronym | Meaning |
 | L | Level |
| L | Low |
| L | Lumen |
| L&C | Laboratory And Checkout |
| L&D | Landing And Deceleration |
| L&L | Launch And Landing |
| L&S | Logistics And SuPport |
| L&T | Laboratory And Test |
| L-BAND | S-Band 390 To 1550 MHz |
| L-L | Line-to-Line |
| L-P | Low Pressure |
| L/D | Length-to-Diameter |
| L/D | Lift-to-Drag (Ratio) |
| L/H | Local Horizontal |
| L/O | Lift-off |
| L/S | Landing Site |
| L/S | LLoad SYstem |
| L/T | Load Test |
| L02 | Liquid Oxygen |
| LA | Lanthanum |
| LA | Launch Abort |
| LA | Launch Aft |
| LA | Launch Area |
| LA | Launch Azimuth |
| LA | Lightning Arrester |
| LA | Low Attitude |
| LAAD | Los Angeles Aircraft Division (Rockwell) |
| LACB | Landing Aids Control Building (SLF At KSC) |
| LACIE | Large Area Crop Inventory Experiment |
| LACIP | Large Area Crop Inventory Program |
| LAGEOS | Laser Geodynamic Satellite |
| LAGS | Launch Abort Guide Simulation |
| LAIR | Liquid Air |
| LAIU | Launch Abort Interface Unit |
| LAN | Local Area Network |
| LANDC | Instrumentation And Communication |
| LAPS | Left Aft Propulsion System (Subsystem) |
| LARC | Langley Research Center (Hampton |
| LARS | Laminar Angular Rate Sensor |
| LARSSYAA | For Aircraft Analysis |
| LARSSYAA | Laboratory For Application Of Remote Sensing System |
| LASCOT | Large Screen Color Television System |
| LASV | Low Altitude Supersonic Vehicle |
| LAT | Large Angle Torque |
| LAT | Latch |
| LAT | Lateral |
| LAT | Latitude |
| LAT | Lot Acceptance Test |
| LATS | LDEF Assembly And Transportation System |
| LB | Launch Boost |
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