| Acronym | Meaning |
| LFO | Low Frequency Oscillator |
| LFOP | Landing And Ferry Operations Panel |
| LFRR | Low Frequency Radio Range |
| LG | Landing Gear |
| LG | Length |
| LGA | Low Gain Antenna |
| LGIU | Laser Gyro Interface Unit |
| LH | Left Hand |
| LH2 | Liquid Hydrogen |
| LH2 | Liquid Hydrogen |
| LHA | Local Hour Angle |
| LHC | Left Hand Circular |
| LHCP | Left Hand Circular Polarization |
| LHCP | Left Hand Circularly Polarized |
| LHE | Liquid Helium |
| LHP | Left Hand Panel |
| LHS | Left Hand Side |
| LI | Lithium |
| LIB | Left Inboard |
| LIC | Load Interface Circuit |
| LID | Leadless Inverted Device |
| LID | Logistics Identification Document |
| LIDAR | Laser-Radar |
| LIE | Left Inboard Elevon |
| LIM | Limit |
| LIMRC | LRU Identification And Maintenance Requirements Catal |
| LIMS | Logistics Inventory Management System |
| LIN | Linear |
| LIN | Liquid Nitrogen |
| LINJET | Liquid Injection Electric Thruster |
| LIOH | Lithium Hydroxide |
| LIOH | Lithium Hydroxide |
| LIQ | Liquid |
| LK | Leak |
| LK | Lock |
| LL | Launch And Landing |
| LL | Launch Left |
| LL | Lever Lock |
| LL | Long Lead |
| LL | Long Line |
| LL | Low Level |
| LL | Lower Left |
| LL | Lower Limit |
| LLCF | Launch And Landing Computational Facilities |
| LLI | Limited Life Item |
| LLIL | Long Leadtime Items List |
| LLOS | Landmark Line-of-Sight |
| LLP | Launch And Landing Project |
| LLPO | Launch And Landing Project Office |
| LLS | Launch And Landing Site |