| Acronym | Meaning |
| LST | Liquid Storage Tank |
| LST | Local Standard Time |
| LSTE | Launch Site Transportation Equipment |
| LSU | International System Of Units |
| LSU | Life Support Umbilical |
| LT | Lead Time |
| LT | Lef T |
| LT | Light |
| LTA | LowerTorsoAssembly |
| LTD | Lift-to-Drag |
| LTD | Limited |
| LTG | Lighting |
| LTG | Linear Tangent Guidance |
| LTM | Lead Time Matrix |
| LUB | Lubricate |
| LUCS | Instrumentation Unit Update Command System |
| LUCS | Instrumentation Update Command SYstem |
| LUS | Liquid Upper Stage |
| LUT | Launcher-Umbilical Tower |
| LV | Launch Vehicle |
| LV | Lift Vector |
| LV | Limit Value |
| LV | Load Vertical |
| LV | Loading Valve |
| LV | Low Voltage |
| LVDC | Launch Vehicle Digital Computer |
| LVDT | Linear Variable Differential Transformer |
| LVDT | Linear Voltage Differential Transformer |
| LVL | Level |
| LVLH | Local Vertical/Local Horizontal |
| LVLH | Local Vertical/local Horizontal |
| LW | Launch Window |
| LWD | Launch WindowDisplay |
| LWD | Left Wing Down |
| LWG | Logistics Working Group |
| LWHS | Lightweight Headset |
| LWHS | Light-Weight Headset |
| LWR | Lower |
| LWS | Lightning Warning System |
| M | Mach |
| M | Maintainability |
| M | Major Cycle |
| M | Male |
| M | Mandatory |
| M | Manual |
| M | Mass |
| M | Matrix |
| M | Mega |
| M | Mercury |
| M | Meter |