| Acronym | Meaning |
| MBPS | Megabits Per Second |
| MBPS | Megabits Per Second |
| MBPS | Million Bits Per Second |
| MBV | Main Base Visit |
| MC | Memory Configuration |
| MC | Mission Capability |
| MC | Mission Completion/Continuation |
| MC&C | Measurement |
| MC&W | Master Caution And Warning |
| MCA | Master ControlAssembly |
| MCA | Maximum Crossing Altitude |
| MCA | Monitoring And Control Assembly |
| MCA | MotorControlAssembly |
| MCA | Multichannel Analyzer |
| MCBF | Mean Cycle Between Failures |
| MCC | Main Combustion Chamber |
| MCC | Main Combustion Chamber |
| MCC | Mission Control Center (JSC) |
| MCC | Motor Control Center (JSC) |
| MCC-DOD | Mission Control Center-DOD |
| MCC-H | Mission Control Center-Houston |
| MCC-H | Mission Control Center-Houston |
| MCC-K | Mission Control Center-Kennedy |
| MCC-NASA | Mission Control Center-NASA |
| MCCC | Mission Control And Computing Center |
| MCCS | Mission Control Center Simulation (System) |
| MCDS | Maintenance Control And Display System |
| MCDS | Multifunction CRT Display System |
| MCDS | Multifunction CRT Display System |
| MCDU | Multifunction CRT Display Unit |
| MCF | Maintenance And Checkout Facility |
| MCF | Mission Control Facility |
| MCIU | Manipulator Controller Interface Unit |
| MCIU | Manipulator Controller Interface Unit |
| MCIU | Master Control And Interface Unit |
| MCIU | Mission Control And Interface Unit |
| MCL | Mass Change Log |
| MCL | Master Configuration List |
| MCLT | Maximum Cruise Level Thrust |
| MCM | MADS Control Module |
| MCN | Master Change Notice |
| MCO | Mission Control Operations |
| MCOP | Mission Control Operations Panel |
| MCP | Master ComputerProgram |
| MCP | Master Change Proposal |
| MCP | Materials Control Plan |
| MCP | Measurements Control Procedure |
| MCP | Mission Control Programmer |
| MCP | Monitoring And Control Panel |
| MCP | Monitoring And Control Panel |