| Acronym | Meaning |
| MPG | Multipoint Grounding |
| MPGHM | Mobile Payload Ground Handling Mechanism |
| MPHE | Material And Personnel Handling EqLjipment |
| MPI | Mission Payload Integration |
| MPIIN | Modification Procurement Instrument Identification |
| MPIIN | Number |
| MPIO | Mission Payload Integration Office |
| MPL | Maintenance Parts List |
| MPL | Manipulation Positioning Latches |
| MPL | Mechanical Parts List |
| MPL | Minimum Power Level |
| MPL | Minimum Power Level (65%) |
| MPLN | Maintenance Planning (Data Base) |
| MPM | Manipulator Positioning Mechanism |
| MPM | Manipulator Positioning Mechanism |
| MPMP | Mass Properties Management Plan |
| MPMSE | Multiuse Payload And Mission Support Equipment |
| MPP | Material Processing Procedure |
| MPPSE | Multipurpose Payload Support Equipment |
| MPR | Maintainability Problem Report |
| MPR | Management Program Review |
| MPR | Mockup Purchase Request |
| MPS | Master Program |
| MPS | Main Propulsion System |
| MPS | Main Propulsion System (Subsystem) |
| MPS | Material Processing Specification |
| MPS | Material Processing System |
| MPS | Materials Processing In Space |
| MPS | Megabits Per Second |
| MPSR | Mission Profile Storage And Retrieval |
| MPSR | Multipurpose Support Room |
| MPSR | Multipurpose Support Room |
| MPST | Multipurpose Support Team |
| MPT | Main Propulsion Test |
| MPTA | Main Propulsion Test Article |
| MPTA | Main Propulsion Test Article |
| MPTF | Main Propulsion Test Facility |
| MPUTER | SimumPuter Simulator |
| MPVA | Main Propellant Valve Actuator |
| MR | Master Reset |
| MR | Material Review |
| MR | Mission Report |
| MR | Mixture Ratio |
| MRA | Mechanical Readiness Assessment |
| MRB | Material Review Board |
| MRC | Measurement Requirements Committee |
| MRCR | Measurement Requirement Change Request |
| MRD | Material Review Disposition |
| MRD | Mission Requirements Document |
| MRDR | Material Review Disposition Record |