| Acronym | Meaning |
| WSDL | Web Services Description Language |
| WSJ | Wall Street Journal |
| WSM | Samoa (ISO 3166 Trigram; From West Samoa) |
| WSMR | White Sands Missile Range (whiz-murr) |
| WST | Water Soluble Tetrazolium (assay) -Samoan Tala (ISO 4217 Currency Code) |
| WSTC | Women Signallers Territorial Corps (WWII UK) |
| WSUS | Windows Server Update Services |
| WSW | West South-West |
| WTB | Wales Tourism Board - Warenterminb?rse Hannover |
| WTC | World Trade Center |
| WTF | What The Fuck? (WTF Could Also Be Considered |
| WTH | What The Hell |
| WTO | World Trade Organization |
| WU | Wabash University - Washington University In St. Louis - Western Union - Windows Update - Work Unit - WU Wien (German Wirtschaftsuniversit?t Wien |
| WV | West Virginia (postal Symbol) |
| WVA | World Veterinary Association |
| WVIAC | West Virginia Intercollegiate Athletic Conference |
| WVR | Women's Volunteer Reserve (WWII UK) |
| WVSC | Women's Volunteer Service Corps (WWII Canada) |
| WVU | West Virginia University |
| WW | See Entry |
| WWE | World Wrestling Entertainment |
| WWF | World Wildlife Fund - World Wrestling Federation |
| WWI | World War I |
| WWII | World War II |
| WWIII | World War III |
| WWJD | What Would Jesus Do? (see WWWD) |
| WWV | Wagner-Werk-Verzeichnis (catalog Of The Works Of Richard Wagner |
| WWW | World Wide Web |
| WWWD | What Would Wellstone Do? (reference To The Late Minnesota Senator Paul Wellstone; See WWJD) |
| WWWF | World Wide Wrestling Federation |
| WXO | Weather [Executive] Officer |
| WY | Wyoming (postal Symbol) |
| WYSIWYG | What You See Is What You Get (pronounced Wizzy-wig. See Entry For Derived Acronyms) |
| WYSIWYP | What You See Is What You Print / What You See Is What You Pay (wizzy-whip) |
| WZ | Swaziland (FIPS 10-4 Country Code) |
| XAF | BEAC (Banque Des ?tats De L'Afrique Centrale) Central Africa CFA (Coop?ration Financi?re En Afrique Centrale) Franc (ISO 4217 Currency Code) |
| XAG | Silver Troy Ounce (ISO 4217 Currency Code) |
| XAU | Gold Troy Ounce (ISO 4217 Currency Code) |
| XBA | European Composite Unit (EURCO; Bonds Market Unit) (ISO 4217 Currency Code) |
| XBB | European Monetary Unit (E.M.U.; Bonds Market Unit) (ISO 4217 Currency Code) |
| XBML | EXtensible Battle Management Language |
| XC | Ninety (in Roman Numerals) |
| XCBL | XML Common Business Library |
| XCD | East Caribbean Dollar (ISO 4217 Currency Code) |
| XE | Xenon |
| XH | Xhosa Language (ISO 639-1 Code) |
| XHO | Xhosa Language (ISO 639-2 Code) |
| XHR | EXtra High Image Resolution - XMLHTTPRequest |
| XHTML | EXtensible Hypertext Markup Language |