| Acronym | Meaning |
| XI | Eleven (in Roman Numerals) |
| XII | Twelve (in Roman Numerals) |
| XIII | Thirteen (in Roman Numerals) |
| XIV | Fourteen (in Roman Numerals) |
| XIX | Nineteen (in Roman Numerals) |
| XL | EXtra Large -Forty (in Roman Numerals) |
| XML | EXtensible Markup Language |
| XMSF | EXtensible Modelling And Simulation Framework |
| XO | ???†‡?…??? ????‰???? (Xristianos Orthodoksos |
| XOF | BCAO (Banque Centrale Des ?tats De L'Afrique De L'Ouest) West African CFA (Communaut? Financi?re D'Afrique) Franc (ISO 4217 Currency Code) |
| XP | EXperience Point (role-playing Games) |
| XPD | Palladium Troy Ounce (ISO 4217 Currency Code) |
| XPF | CFP Franc (ISO 4217 Currency Code) |
| XPT | Platinum Troy Ounce (ISO 4217 Currency Code) |
| XRML | EXtensible Rights Markup Language |
| XS | Xiaolin Showdown |
| XSL | EXtensible Style Language |
| XUL | XML User Interface Language |
| XV | Fifteen (in Roman Numerals) |
| XVI | Sixteen (in Roman Numerals) |
| XVII | Seventeen (in Roman Numerals) |
| XVIII | Eighteen (in Roman Numerals) |
| XX | Twenty (in Roman Numerals) |
| XXX | Hardcore Pornography (film Rating) - Thirty (in Roman Numerals) |
| Y | Yocto |
| Y | Yotta - Yttrium |
| Y2K | Year Two Thousand |
| YA | Yoctoampere |
| YA | Yottaampere -Young Adult |
| YA | Yottayear |
| YABPR | Yet Another Brother Pat Rant |
| YAC | Youth-Adult Committee |
| YAP | Young Aspiring Professional |
| YB | Youcef Benzouada (Southern Algerian Name) |
| YB | Ytterbium |
| YC | Yoctocoulomb |
| YC | Yottacoulomb |
| YD | People's Democratic Republic Of Yemen (ISO 3166 Digram |
| YE | Yemen (ISO 3166 Digram) |
| YEM | Yemen (ISO 3166 Trigram) - Manitowaning/Manitoulin East Municipal Airport IATA Airport Code |
| YER | Yemeni Rial (ISO 4217 Currency Code) |
| YF | Yoctofarad |
| YF | Yottafarad |
| YG | Yoctogram |
| YG | Yottagram |
| YGCO | Yamaneko Group Of Comet Observers |
| YGO | Yu-Gi-Oh! |
| YH | Yoctohenry |
| YH | Yottahenry |
| YHBT | You Have Been Trolled |