| Acronym | Meaning |
| YI | Serbia And Montenegro (deprecated FIPS 10-4 Country Code |
| YI | Yiddish Language (ISO 639-1 Code) |
| YI | Yobi |
| YID | Yiddish Language (ISO 639-2 Code) |
| YIPPIE | Youth International Party + Suffix |
| YJ | Yoctojoule |
| YJ | Yottajoule |
| YK | Yoctokelvin |
| YK | Yottakelvin |
| YL | Yoctolitre |
| YL | Yottalitre |
| YM | Yemen (FIPS 10-4 Country Code) -Your Magazine (originally Young Miss |
| YM | Yoctometre |
| YM | Yottametre |
| YMCA | Young Men's Christian Association |
| YMD | People's Democratic Republic Of Yemen (ISO 3166 Trigram |
| YMMV | Your Mileage May Vary |
| YN | Yoctonewton |
| YN | Yottanewton |
| YO | Former Yugoslavia (NATO Country Code |
| YO | Yoruba Language (ISO 639-1 Code) |
| YOR | Yoruba Language (ISO 639-2 Code) |
| YPA | Yards Per Pass Attempt (football Statistic) |
| YS | Yoctosecond |
| YS | Yoctosiemens |
| YS | Yottasecond |
| YS | Yottasiemens |
| YSA | Youth Service America - Young Socialist Alliance |
| YSI | Young Scots For Independence |
| YT | Mayotte (ISO 3166 Digram) - Yottatesla - Yukon Territory (postal Symbol) |
| YT | Yoctotesla |
| YTD | Year-To-Date |
| YTM | Yield To Maturity |
| YTS | Youth Training Scheme |
| YU | York University -former Yugoslavia (ISO 3166 Digram |
| YUG | Former Yugoslavia (ISO 3166 Trigram |
| YUPPIE | Young Urban Professional + Suffix |
| YV | Yoctovolt |
| YV | Yottavolt |
| YW | Yoctowatt |
| YW | Yottawatt |
| YWCA | Young Women's Christian Association |
| YYH | YuYu Hakusho |
| Z | Zepto |
| Z | Zetta |
| ZA | South Africa (ISO 3166 Digram) - Zambia (FIPS 10-4 Country Code) - Zettaampere |
| ZA | Zeptoampere |
| ZA | Zhuang Language (ISO 639-1 Code) |
| ZAF | South Africa (ISO 3166 Trigram) |
| ZAMS | Zero Age Main Sequence |