| Acronym | Meaning |
 | CAC | California Association Of Criminalists - Chronic Asymptomatic [Disease] Carrier |
| CACM | Communications Of The ACM |
| CAD | Canadian Dollar (ISO 4217 Currency Code) -Computer-Aided Design - Computer-Aided Dispatch |
| CADCAM | Computer-Aided Design/Computer-Aided Manufacturing |
| CADMID | Concept |
| CADPAT | CAnadian Disruptive PATtern |
| CAE | Canadian Aviation Electronics (originally) - Certificate In Advanced English |
| CAEN | Close Action Engagement (constructive Simulation) |
| CAF | Central African Republic (ISO 3166 Trigram) -Confederation Of African Football (or French Conf?d?ration Africaine De Football) |
| CAFAD | Combined Arms For Air Defence |
| CAFDE | Canadian Association Of Film Distributors And Exporters - Computer Aided Federation Development Environment |
| CAFE | Corporate Average Fuel Economy Standard |
| CAI | Computer Assisted Instruction |
| CAIR | Council On American-Islamic Relations |
| CALABARZON | A Region In The Philippines: CAvite |
| CALL | (U.S.) Center For Army Lessons Learned |
| CAM | Chemical Agent Monitor - Computer-Aided Manufacturing |
| CAMRA | CAMpaign For Real Ale |
| CAN | Canada (ISO 3166 Trigram) |
| CANA | Convulsive Antidote |
| CANDU | CANada Deuterium Uranium (nuclear Reactor Design) |
| CANOLA | Canadian Oil |
| CAP | Combat Air Patrol - Civil Air Patrol - Common [Operating/Operational] Air Picture - Crisis Action Procedures - Common Agricultural Policy |
| CAPES | CAPability Evaluation System -Combined Arms Planning And Execution System |
| CARE | Community Database On Accidents On The Roads In Europe -Cooperative For Aid And Relief Everywhere (originally Cooperative For American Remittances To Europe) |
| CARMONETTE | Computerized Monte Carlo Simulation |
| CARP | Computed Air Release Point |
| CART | Championship Auto Racing Teams (now Defunct) |
| CAS | Chemical Abstracts Service - Chief Of The Air Staff - Close Air Support |
| CASE | Cellular Ammunition Storage Equipment - Computer-Aided Software Engineering |
| CASS | Command Activated Sonobuoy System |
| CASTFOREM | Combined Arms And Support Task FORce Evaluation Model |
| CASTOR | Canadian Automatic Small Telescopes For Orbital Research |
| CAT | Community Acceptance Testing - Computer-Assisted (or Axial) Tomography |
| CAT | Catalan Language (ISO 639-2 Code) |
| CATK | Counterattack |
| CATS | Computer Active Technology Suspension |
| CATT | Combined Arms Tactical Trainer |
| CAV | Cavalry |
| CAVOK | Ceiling And Visibility OK (Kav-okay) |
| CAW | Canadian Auto Workers Trade Union |
| CB | Cambodia (FIPS 10-4 Country Code) -Citizens' Band Radio |
| CBASSE | Commission On Behavioral And Social Sciences And Education (sea Bass) |
| CBC | Canadian Broadcasting Corporation - Christmas Bird Count - Cipher-Block Chaining - Cornering Brake Control |
| CBE | Commander Of The Order Of The British Empire - Cab Beside Engine (see Truck) |
| CBLA | Comparative Bullet Lead Analysis |
| CBM | Many |
| CBML | Coalition Battle Management Language |
| CBOL | Consortium For The Barcode Of Life |
| CBR | Case-Based Reasoning |
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