| Acronym | Meaning |
 | CPPCC | Chinese People's Political Consultative Conference |
| CPR | Canadian Pacific Railway - CardioPulmonary Resuscitation |
| CPSM | Continuous Phase Shift Modulation |
| CPSU | Communist Party Of The Soviet Union |
| CPT | Contingency Planning Team |
| CPU | Central Processing Unit |
| CPV | Cape Verde (ISO 3166 Trigram) |
| CPX | Command Post EXercise |
| CQ | Carrier Qualification - Central Queensland - Charge Of Quarters - Congressional Quarterly - Constellation Airlines (IATA Airline Designator) - Northern Mariana Islands (FIPS 10-4 Territory Code) |
| CQD | Close Quarters Drill (Morse Distress Code Preceding SOS: CQ Calling All Stations |
| CR | Chrome |
| CR | Coral Sea Islands (FIPS 10-4 Territory Code) - Costa Rica (ISO 3166 Digram) |
| CR | Cree Language (ISO 639-1 Code) |
| CRAM | Combined Radiometric Correction Model |
| CRC | Central RTI Component - Chemical Rubber Company - Christian Reformed Church - Control And Reporting Centre -Costa Rican Col›n (ISO 4217 Currency Code) -Cyclic Redundancy Check |
| CRD | Capstone Requirements Document |
| CRE | Cree Language (ISO 639-2 Code) |
| CREB | Cyclic AMP-response Element Binding (protein) |
| CREEP | Committee To Re-Elect The President |
| CRI | Costa Rica (ISO 3166 Trigram) |
| CRIPL | Consolidated Remain-In-Place List |
| CRM | Cardiac Rhythm Management - Customer Relationship Management |
| CRP | Committee To Re-elect The President - Control And Reporting Post |
| CRT | Cardiac Resynchronization Therapy - Cathode Ray Tube - Chinese Remainder Theorem |
| CRTC | Canadian Radio-television And Telecommunications Commission |
| CS | Combat Support - Computer Scientist -Costa Rica (FIPS 10-4 Country Code) - Serbia And Montenegro (ISO 3166 Digram) |
| CS | Caesium |
| CS | Czech Language (ISO 639-1 Code) |
| CSA | Canadian Space Agency - Canadian Standards Association - Child Support Agency - Command Staff Advisor - Community-supported Agriculture - Confederate States Of America - Corps Storage Area -Czech Airlines |
| CSAR | Combat Search And Rescue (seessar) |
| CSC | Closed Spacelike Curve (relativity) - Computer Security Centre |
| CSEAL | Combat Systems Engineering And Analysis Laboratory (see-seal) |
| CSERIAC | (U.S. DoD) Crew Systems Ergonomics Information Analysis Center |
| CSG | Corps Support Group |
| CSI | See Entry |
| CSICOP | Committee For The Scientific Investigation Of Claims Of The Paranormal (became The Committee For Skeptical Inquiry In 2006) |
| CSIP | Commercial Stable Image Platform (AMD) |
| CSIS | Canadian Security Intelligence Service (seessiss) -(U.S.) Center For Strategic & International Studies |
| CSK | Czechoslovakia (ISO 3166 Trigram; Obsolete Since 1993) |
| CSL | U.K. Central Science Laboratory |
| CSPI | Center For Science In The Public Interest |
| CSR | Control Supply Rate |
| CSRC | Conflict Studies Research Centre |
| CSRF | Cross-Site Request Forgery |
| CSS | Cascading Style Sheets - Catalina Sky Survey - Central Security Service - Combat Service Support - Confederate States Ship - Content-scrambling System - Cross-site Scripting |
| CSSCS | Combat Service Support Control System |
| CST | Central Standard Time (UTC-6 Hours) |
| CT | Canton And Enderbury Islands (ISO 3166 Digram; Merged Into KI In 1984) - Central African Republic (FIPS 10-4 Country Code) - Connecticut (postal Symbol) |
| CTBT | Comprehensive [Nuclear] Test Ban Treaty |
| CTC | Closed Timelike Curve (relativity) - (U.S.) Combat Training Center |
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