| Acronym | Meaning |
| FOOP | Friends Of Organ Pipes (Volunteer Group) |
| FOR | Field Of Regard - Frame Of Reference |
| FORTRAN | The IBM Mathematical FORmula TRANslating System (programming Language) |
| FOS | Family Of Systems |
| FOS | Florida Ornithological Society - Full Operational Status |
| FOTA | Fellow Of The Orthodontic Technicians Association |
| FOV | Field Of View |
| FP | French Polynesia (FIPS 10-4 Territory Code) |
| FPF | Final Protective Fire |
| FPS | Fire Prevention System - First Person Shooter (computer/video Games) |
| FPS | Frames Per Second (motion Pictures |
| FQ | Baker Island (FIPS 10-4 Territory Code) - French Southern And Antarctic Territories (ISO 3166 Digram; Obsolete 1979) |
| FQDN | Fully Qualified Domain Name |
| FR | France (FIPS 10-4 Country Code; ISO 3166 Digram) |
| FR | Francium |
| FR | French Language (ISO 639-1 Code) |
| FRA | Federal Railroad Administration -France (ISO 3166 Trigram) |
| FRA | French Language (ISO 639-2 Code) |
| FRAGO | Fragmentary Order (military) |
| FRCP | Federal Rules Of Civil Procedure |
| FRICBM | Full Range ICBM |
| FRO | Faroe Islands (ISO 3166 Trigram) |
| FRS | Fellow Of The Royal Society - U.S. Federal Reserve System |
| FRSA | Fellow Of The Royal Society Of Art |
| FRY | Federal Republic Of Yugoslavia |
| FRY | West Frisian Language (ISO 639-2 Code) |
| FS | Femtosecond |
| FS | Femtosiemens |
| FS | Fire Support (military) -French Southern And Antarctic Territories (FIPS 10-4 Territory Code) |
| FSA | Fire Support Area - UK Food Standards Agency - Functional Solution Analysis |
| FSB | Federal'naya Sluzhba Bezopasnosti Rossiyskoi Federatsii (???????????? ??????? ????????????? ??????????? ?????????? |
| FSC | Federal Supply Classification -Forest Stewardship Council (ecological Pressure Group) |
| FSCL | Fire Support Co-ordination Line |
| FSE | Fire Support Element |
| FSF | Free Software Foundation |
| FSH | Follicle Stimulating Hormone |
| FSI | Fuel Stratified Injection |
| FSK | Federal'naya Sluzhba Kontrrazvedki (???????????? ??????? ?????????????? |
| FSM | Federated States Of Micronesia (ISO 3166 Trigram) |
| FSO | Fire Support Officer - Flotilla Staff Officer - Foreign Service Officer |
| FSS | Fire Support Station |
| FSSP | Families Of Structurally Similar Proteins |
| FST | Finance Support Team - Finlands Svenska Television (Finland's Swedish-language Television) - Future Soviet Tank (Cold War Era) |
| FSTC | Foreign Science Technology Center (now NGIC) |
| FSV | Fire Support Vehicle - Fisheries Survey Vessel - Flexible Sender Validation - Fort St. Vrain - Fu Ball Und Sportverein (German Football And Sport Association |
| FT | Femtotesla |
| FTC | Federal Trade Commission |
| FTE | Full Time Equivalent |
| FTL | Faster Than Light |
| FTP | File Transfer Protocol |