| Acronym | Meaning |
| ADW | Air Defence Warning |
| AE | Armed Forces Africa/Canada/Europe/Middle East (postal Symbol) - United Arab Emirates (ISO 3166 Digram; FIPS 10-4 Country Code) |
| AE | Avestan Language (ISO 639-1 Code) |
| AED | United Arab Emirates Dirham (ISO 4217 Currency Code) |
| AEF | American Expeditionary Force |
| AEGIS | Airborne Early Warning Ground Environment Interface Segment (fake Etymology) |
| AEI | T -Army Enterprise Infostructure-Transport |
| AEQ. | Aequalis (Latin |
| AESR | Aeronautical Equipment Service Record |
| AET | After Extra Time (Football) |
| AET. | Aetatis (Latin |
| AEW | Airborne Early Warning - Airborne Electronic Warfare |
| AF | Afghanistan (FIPS 10-4 Country Code; ISO 3166 Digram) -Air Force |
| AF | Afrikaans Language (ISO 639-1 Code) |
| AF | Attofarad |
| AFA | U.S. Air Force Academy |
| AFAIC | As Far As I'm Concerned |
| AFAICT | As Far As I Can Tell |
| AFAIK | As Far As I Know |
| AFAIR | As Far As I Remember/Recall |
| AFATDS | Advanced Field Artillery Tactical Data System |
| AFC | American Football Conference - Asian Football Confederation |
| AFCEA | Armed Forces Communications And Electronics Association |
| AFDB | African Development Bank |
| AFES | Automatic Fire Extinguishing System |
| AFG | Afghanistan (ISO 3166 Trigram) |
| AFI | French Territory Of The Afars And Issas (ISO 3166 Trigram; Obsolete Since 1977) - Agencia Federal De Investigaci›nes (M?xico) |
| AFIS | Automated Fingerprint Identification System - American Forces Information Service |
| AFIST | Abrams Full Crew Interactive Skills Trainer |
| AFJ | April Fool's Joke |
| AFK | Away From Keyboard (Internet Chat Abbreviation) |
| AFL | CIO -American Federation Of Labor - Congress Of Industrial Organizations |
| AFL | American Federation Of Labor - American Football League - Arena Football League - Australian Football League |
| AFM | Army Field Manual (UK; The U.S. More Frequently Uses Just FM) - Atomic Force Microscope - Aviation Fleet Maintenance |
| AFN | Afghani (ISO 4217 Currency Code) |
| AFO | Association Of Field Ornithologists |
| AFOSR | U.S. Air Force Office Of Scientific Research |
| AFQT | Armed Forces Qualification Test |
| AFR | Afrikaans Language (ISO 639-2 Code) |
| AFRC | Air Force Reserve Command |
| AFRL | Air Force Research Laboratory |
| AFROTC | Air Force Reserve Office Training Corps |
| AFRRI | (U.S.) Armed Forces Radiobiology Research Institute |
| AFRTS | Armed Forces Radio And Television Service |
| AFS | Active Front Steering - Air Facility Sub-System - Amniotic Fluid-derived Stem Cell |
| AFS&A OR AFSA | U.S. Air Force Studies And Analysis |
| AFSC | U.S. Air Force Staff College (obsolete; Replaced With JFSC). - U.S. Air Force Systems Command |
| AFSCN | U.S. Air Force Satellite Control Network |
| AFSPC | Air Force Space Command |
| AFT | American Farmland Trust |