| Acronym | Meaning |
| L | Fifty (in Roman Numerals) -Label - Lap - Large - Laser (US Military Aircraft Basic Mission Designation) - Latin - Left -Litre -Low (transmissions) |
| L.S. | Lectori Salutem (Latin |
| LA | Lanthanum |
| LA | Laos (FIPS 10-4 Country Code; ISO 3166 Digram) -Los Angeles -Louisiana (postal Symbol) |
| LA | Latin Language (ISO 639-1 Code) |
| LAAS | Local Area Augmentation System - Los Angeles Astronomical Society |
| LAB | Logistics Assault Base |
| LABVIEW | Laboratory Virtual Instrumentation Engineering Workbench |
| LACMA | Los Angeles County Museum Of Art |
| LAD | Laser Aiming Device |
| LADW | Local Air Defence Warning |
| LAESI | Local Authority & Emergency Service Information |
| LAK | Laotian Kip (ISO 4217 Currency Code) |
| LAMP | Linux |
| LAN | Local Area Network |
| LANL | Los Alamos National Laboratory |
| LAO | Lao Language (ISO 639-2 Code) |
| LAO | Laos (ISO 3166 Trigram) |
| LAPD | Los Angeles Police Department |
| LAR | Light Armoured Reconnaissance - Logistics Assistance Representative |
| LARC | Livermore Advanced Research Computer (cf. LLNL) |
| LARP | Live-Action Role-Playing |
| LAS | McCarran International Airport (Las Vegas |
| LASER | Light Amplification By Stimulated Emission Of Radiation (cf. Maser) |
| LAT | Lowest Astronomical Tide (nautical Charts) |
| LAT | Latin Language (ISO 639-2 Code) |
| LATA | Local Access Transport Area |
| LAV | Land Assault Vehicle - Light Armoured Vehicle - Lymphadenopathy-Associated Virus |
| LAV | Latvian Language (ISO 639-2 Code) |
| LAW | Light Antitank Weapon |
| LAX | Los Angeles International Airport |
| LB | Lebanon (ISO 3166 Digram) |
| LB | Pound (Latin Librum) - Luxembourgish Language (ISO 639-1 Code) |
| LBH | Light Battlefield Helicopter - Lyman-Birge-Hopfield Bands |
| LBJ | Lady Bird Johnson - Light Bulb Joke - Little Beagle Johnson (LBJ's Dog) - Lyndon Baines Johnson |
| LBN | Lebanon (ISO 3166 Trigram) |
| LBNL | Lawrence Berkeley National Laboratory |
| LBP | Lebanese Pound (ISO 4217 Currency Code) |
| LBR | Liberia (ISO 3166 Trigram) |
| LBS | Location-Based Services |
| LBW | Leg Before Wicket |
| LBY | Libya (ISO 3166 Trigram) |
| LC | Line Of Contact -Saint Lucia (ISO 3166 Digram) |
| LC2IEDM OR LC?IEDM | Land C2IEDM (q.v.) |
| LCA | Saint Lucia (ISO 3166 Trigram) |
| LCC | Land Component Commander |
| LCCP | Light Contingency Communications Package |
| LCD | Liquid Crystal Display |
| LCE | Leaving Certificate Examination - Load Carrying Equipment - London Commodity Exchange |
| LCM | Least/Lowest Common Multiple |