| Acronym | Meaning |
| PME | Professional Military Education |
| PMID | PubMed Identifier |
| PMMA | PolyMethylMethAcrylate |
| PMOS | P-type/Positive Metal-Oxide-Semiconductor Transistor (pee-moss) |
| PMSC | NATO Political-Military Steering Committee On Partnership For Peace |
| PN | Petanewton - Pitcairn Islands (ISO 3166 Digram) |
| PN | Piconewton |
| PNAC | Project For The New American Century |
| PNF | Pilot Not Flying (aviation) |
| PNG | Papua New Guinea (ISO 3166 Trigram) -Portable Network Graphic |
| PNH | Paroxysmal Nocturnal Hemoglobinuria - Police Nationale D'Ha?ti (French |
| PNP | Partido Nuevo Progresista - Plug 'N' Play/Pray - Positive Negative Positive |
| PNS | Pensacola |
| PNVS | Pilot Night Vision Sensor |
| PO | Dust Devil (METAR Code) -per Os (Latin |
| PO | Polonium |
| POCD | Post-Operative Cognitive Dysfunction |
| POD | Plain Old Documentation |
| POD | Port Of Debarkation |
| POE | Perl Object Environment -Port Of Embarkation |
| POETS | Portable Occultation |
| POG | Passionfruit |
| POGO | Project On Government Oversight |
| POI | Program Of Instruction |
| POK | Plane Of Knowledge |
| POL | Petroleum, Oil, And Lubricant |
| POL | Polish Language (ISO 639-2 Code) |
| POLAD | Political Advice |
| POM | Program Objective Memorandum - PolyOxyMethylene |
| POMDP | Partially Observable Markov Decision Process |
| POP | Point Of Presence - Post Office Protocol - Progesterone Only Pill |
| POR | Proposed Operational Requirement |
| POR | Portuguese Language (ISO 639-2 Code) |
| POS | Point Of Sale Terminal /Retail Industry Transaction Computers. |
| POSH | Port Outbound Starboard Home (alleged) |
| POSSLQ | Person Of The Opposite Sex Sharing Living Quarters |
| POT | Plane Of Tranquility |
| POTS | Plain Old Telephone Service (cf. PANS) - Postural Orthostatic Tachycardia Syndrome |
| POW | Prisoner Of War |
| PP | Papua New Guinea (FIPS 10-4 Country Code) -Passage Point - Per Procurationem (Latin |
| PPA | Parahippocampal Place Area - PolyPhthalAmide |
| PPASC | (U.S.) Plans And Program Analysis Support Center |
| PPCLI | Princess Patricia's Canadian Light Infantry (regiment) |
| PPLI | Precise Participant Location & Identification |
| PPM | Parts Per Million |
| PPM | Parts Per Million |
| PPO | PolyPhenylene Oxide |
| PPP | Point-to-Point Protocol - Purchasing Power Parity |
| PPQ | Pulses Per Quarter (used In Music Programming |
| PPQN | Pulses Per Quarter Note (ditto) |