| Acronym | Meaning |
| SGD | Singapore Dollar (ISO 4217 Currency Code) |
| SGML | Standard Generalized Markup Language |
| SGP | Singapore (ISO 3166 Trigram) |
| SGS | South Georgia And The South Sandwich Islands (ISO 3166 Trigram) -Svalbard Ground Station (Landsat) - Soci?t? G?n?rale De Surveillance |
| SH | Saint Helena (ISO 3166 Digram) -SONATRACH (Algerian Petroleum Company) |
| SH | Serbo-Croatian Language (ISO 639-1 Code) |
| SHAC | Stop Huntingdon Animal Cruelty |
| SHAPE | Supreme Headquarters Allied Powers Europe |
| SHF | Super High Frequency |
| SHN | Saint Helena (ISO 3166 Trigram) |
| SHOALS | Scanning Hydrographic Operational Airborne Lidar Survey |
| SHORAD | Short Range Air Defence |
| SHORADEZ | SHORAD Engagement Zone |
| SHP | Saint Helena Pound (ISO 4217 Currency Code) |
| SHRA | Rain Showers (METAR Code) |
| SHSN | Snow Showers (METAR Code) |
| SI | Silicon |
| SI | Sinhalese Language (ISO 639-1 Code) |
| SI | Slovenia (ISO 3166 And FIPS 10-4 Country Code Digram) -Socialist International - Sports Illustrated - Syst?me International (French |
| SIA | Singapore Airlines (ICAO Code) |
| SIAM | Society For Industrial And Applied Mathematics |
| SIC | Standard Industrial Classification |
| SICS | Swedish Institute Of Computer Science |
| SIDS | Sudden Instant Death Syndrome |
| SIF | Selective Identification Feature |
| SIFF | Successor IFF |
| SIG | .signature (UNIX Shell/Internet Standard File Name) -Special Interest Group |
| SIGCAT | Special Interest Group For CD-ROM Applications And Technology |
| SIGINT | Signals Intelligence |
| SIGMET | Significant Meteorological Information |
| SIIT | Saskatchewan Indian Institute Of Technologies (Canadian University) - Sirindhorn International Institute Of Technology (Thai University) - Stateless IP/ICMP Translation Algorithm |
| SIMAC | Semantic Interaction With Music Audio Contents |
| SIMLAS | Soldier Integrated Multipurpose Laser System |
| SIMM | Single In-line Memory Module |
| SIMNET | SIMulator NETwork |
| SIMP | Strongly Interacting Massive Particle |
| SIMPLE | Satellite Interactive Multimedia Platform For Low-cost Earth Stations - Savings Incentive Match Plan For Employees (as Used In SIMPLE IRA) - Standard Interface For Multiple Platform Link Evaluation (NATO STANAG 5602) |
| SIN | Social Insurance Number (Canada) |
| SIN | Sinhalese Language (ISO 639-2 Code) |
| SINCGARS | SINgle Channel Ground And Airborne Radio System |
| SIP | Session Initiation Protocol - State Implementation Plan - System Improvement Program - Systematic Investment Plan |
| SIPP | Self-Invested Personal Pension |
| SIS | Silicon Integrated Systems |
| SIS | UK Secret Intelligence Service (also Known As MI6) |
| SISO | Simulation Interoperability Standards Organization - Society Of Independent Show Organizers |
| SIW | Simulation Interoperability Workshop |
| SIYSS | Stockholm International Youth Science Seminar |
| SJ | Svalbard And Jan Mayen (ISO 3166 Digram) -Societas Iesu (Latin: The Society Of Jesus |
| SJA | Staff Judge Advocate (military Law) |
| SJC | Supreme Judicial Court Of Massachusetts (note: The Highest Court In The State Of Maine Is Also Called The Supreme Judicial Court) |