| Acronym | Meaning |
| SRSP | Science And Religion In Schools Project |
| SS | Sand Storm (METAR Code) -Schutzstaffel (Nazi Elite Praetorian Guard) -U.S. Secret Service - Spanish Ship - Stainless Steel - Stockholm Skins -Submarine (US Navy Hull Classification) -Super Sport - Surface-to-Surface (missile) |
| SS | Swati Language (ISO 639-1 Code) |
| SSA | Cargo Submarine (US Navy Hull Classification) |
| SSBN | Nuclear-Powered Ballistic Missile Submarine (US Navy Hull Classification) |
| SSC | Safe |
| SSCCATAGAPP | Singles |
| SSDC | U.S. Space And Strategic Defense Command |
| SSDD | Same Shit |
| SSE | South South-East -Streaming SIMD Extensions |
| SSG | Guided Missile Submarine (retired US Navy Hull Classification) |
| SSGN | Nuclear-Powered Guided Missile Submarine (US Navy Hull Classification) |
| SSH | Saffir-Simpson Hurricane Scale |
| SSK | Hunter-Killer Submarine (retired US Navy Hull Classification) |
| SSKP | Single-Shot Kill Probability |
| SSM | Surface-to-Surface (Guided) Missile |
| SSN | Nuclear-Powered Attack Submarine (US Navy Hull Classification) -SIM Serial Number - Social Security Number - Socialist Solidarity Network - Subsystem Number (SCCP |
| SSNW | Same Shit |
| SSO | Submarine Oiler (retired US Navy Hull Classification) |
| SSP | Submarine Transport (retired US Navy Hull Classification) |
| SSR | Radar Picket Submarine (retired US Navy Hull Classification) -Solid State Recorder |
| SSRI | Selective Serotonin Reuptake Inhibitor - Social Systems Research Institute |
| SSRN | Nuclear-Powered Radar Picket Submarine (retired US Navy Hull Classification) |
| SSS | Siding Spring Survey - Side Side Side (an Acronym For Remembering Congruent Triangles) |
| SST | SuperSonic Transport -Training Submarine (US Navy Hull Classification) - Saturated Suction Temperature (refrigeration Cycles) |
| SSTO | Single-Stage To Orbit |
| SSV | Soft-Skinned Vehicle (i.e |
| SSW | South South-West |
| SSW | Swati Language (ISO 639-2 Code) |
| ST | Saint Lucia (FIPS 10-4 Country Code) - S?o Tom? And Prncipe (ISO 3166 Digram) |
| ST | Sotho Language (ISO 639-1 Code) |
| STA | Scheduled Time Of Arrival - Surveillance And Target Acquisition |
| STAG | (U.S.) Strategy And Tactics Group |
| STAGE | Scenario Toolkit And Generation Environment |
| STANAG | (NATO) Standardisation Agreement |
| STAR | Scientific And Technical Aerospace Reports (NASA) - Simulation Of Tactical Alternative Responses - Special Threat Analysis And Recognition |
| STAT | Signal Transducers And Activators Of Transcription (cell Biology) - Special Tertiary Admissions Test (Australia) |
| STC | Superior Temporal Cortex |
| STD | S?o Tom? And Prncipe Dobra (ISO 4217 Currency Code) -Sexually Transmitted Disease |
| STDM | Statistical Time Division Multiplexing |
| STENTOR | Satellite De T?l?communications Pour Exp?rimenter De Nouvelles Technologies En Orbite (French |
| STFU | Shut The Fuck Up |
| STH | Sonic The Hedgehog |
| STI | Sexually Transmitted Infection - Subaru Tecnica International |
| STK | Satellite Tool Kit |
| STM | Short Term Memory |
| STOL | Short Take-Off And Landing |
| STOVL | Short Take-Off And Vertical Landing |
| STP | S?o Tom? And Prncipe (ISO 3166 Trigram) -Standard Temperature And Pressure |
| STR | Short Tandem Repeat (DNA Analysis) |