| Acronym | Meaning |
| SY | Syria (ISO 3166 And FIPS 10-4 Country Code Digram) |
| SYC | Seychelles (ISO 3166 Trigram) |
| SYP | Syrian Pound (ISO 4217 Currency Code) |
| SYR | Syria (ISO 3166 Trigram) |
| SYSML | System Modeling Language |
| SZ | Swaziland (ISO 3166 Digram) - Switzerland (FIPS 10-4 Country Code) |
| SZL | Swaziland Lilangeni (ISO 4217 Currency Code) |
| T | Tera - Tesla - Tritium |
| T/O | Theatre Of Operations |
| TA | Target Acquisition - Teaching Assistant -Tera-ampere -Territorial Army (UK) -Tristan Da Cunha (ISO 3166 Digram) |
| TA | Tamil Language (ISO 639-1 Code) |
| TA | Tantalum |
| TAA | Transparency Anti-Aliasing |
| TAACOM | U.S. Theater Army Area Command |
| TAADCOORD | Theatre Army Air Defence Co-ordinator |
| TAAR | Trace Amine-Associated Receptor |
| TAC | U.S. Tactical Air Command (1946-1992) |
| TACAMO | Take Charge And Move Out (U.S. Military) |
| TACAN | Tactical Air Navigation |
| TACC | Tactical Air Control Centre - (USAF) Tanker Airlift Control Center |
| TACCO | Tactical Coordinator |
| TACCSF | U.S. Theater Aerospace Command & Control Simulation Facility |
| TACDAR | Tactical Detection And Reporting |
| TACP | Tactical Air Control Party - Technology Applications Certification Program |
| TACSOP | Tactical SOP (Standing Operating Procedure) |
| TADIL | Tactical Digital Information Link |
| TADL | Tactical Air Data Link (taddle) |
| TADSS | Training Aids |
| TAH | Tahitian Language (ISO 639-2 Code) |
| TAI | Target[ed] Area Of Interest |
| TAJ | Tom And Jerry |
| TAJT | Tom And Jerry Tales |
| TALES | Technical Advice And Lexicon For Enabling Simulation |
| TAM | Tamil Language (ISO 639-2 Code) |
| TANJ | There Ain't No Justice (used As Expletive In The Ringworld Novels) |
| TANP | Terrain-Aware Network Planner |
| TANSTAAFL | There Ain't No Such Thing As A Free Lunch (coined By Author Robert A. Heinlein In His The Moon Is A Harsh Mistress) |
| TARDIS | Time And Relative Dimensions In Space (from Doctor Who) |
| TAROT | T?lescope ? Action Rapide Pour Les Objets Transitoires (French |
| TAS | Tasmania (postal Symbol) |
| TASER | Thomas A. Swift's Electric Rifle |
| TASM | Tactical Air-to-Surface Missile |
| TAT | Tourism Authority Of Thailand |
| TAT | Tatar Language (ISO 639-2 Code) |
| TATP | TriAcetone TriPeroxide |
| TATT | Tired All The Time (medical Diagnosis In-joke) |
| TB | Tuberculosis |
| TB | Terbium |
| TBA | To Be Announced |
| TBBPA | TetraBromoBisPhenol-A |