| Acronym | Meaning |
 | DESC | Defense Energy Support Center |
| DFAS | Defense Finance And Accounting Service |
| DHS | Department Of Homeland Security |
| DIA | Defense Intelligence Agency |
| DINFOS | Defense Information School |
| DISA | Defense Information Systems Agency |
| DLA | Defense Logistics Agency |
| DLAPS | Defense Logistics Agency Publishing System |
| DLIS | Defense Logistics Information Service |
| DLSA | Defense Legal Services Agency |
| DMA | Defense Mapping Agency (replaced By NIMA) |
| DMDC | Defense Manpower Data Center |
| DMS | Defense Mapping School (changed To NGS) |
| DNFSB | Defense Nuclear Facilities Safety Board |
| DNSC | Defense National Stockpile Center |
| DOC | Department Of Commerce |
| DOD | Department Of Defense |
| DODEA | Department Of Defense Education Activity |
| DODISS | DoD Index Of Specifications And Standards |
| DODSSP | Single Stock Point For Specifications And Standards |
| DOE | Department Of Energy |
| DOI | Department Of The Interior |
| DOJ | Department Of Justice |
| DOL | Department Of Labor |
| DORRA | DLA Office Of Operations Research And Resource Analysis |
| DOS | Department Of State |
| DOT | Department Of Transportation |
| DPC | Domestic Policy Council |
| DPL | Denied Persons List |
| DPMO | Defense Prisoner Of War/Missing Personnel Office |
| DRMS | Defense Reutilization And Marketing Service |
| DSCA | Defense Security Cooperation Agency |
| DSS | Defense Security Service |
| DTIC | Defense Technical Information Center |
| DTRA | Defense Threat Reduction Agency |
| EAR | Export Administration Regulations |
| EBSA | Employee Benefits Security Administration |
| ECA | Bureau Of Educational And Cultural Affairs |
| ECAB | Employees' Compensation Appeals Board |
| ECI | National Institute On Early Childhood Development And Education |
| ECIE | Executive Council On Integrity And Effiency |
| ECOSOC | Economic And Social Council |
| ECP | Emergency Conservation Program |
| ED | Department Of Education |
| EDA | Economic Development Administration |
| EDGAR | Electronic Data Gathering |
| EEOC | Equal Employment Opportunity Commission |
| EHP | Environmental Health Perspectives |
| EIA | Energy Information Administration |
| EIS | Epidemic Intelligence Service |
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