| Acronym | Meaning |
 | MBDA | Minority Business Development Agency |
| MCHB | Maternal And Child Health Bureau |
| MCTL | Militarily Critical Technologies List |
| MEDPAC | Medicare Payment Advisory Commission |
| MESH | Medical Subject Headings |
| MIGA | Multilateral Investment Guarantee Agency |
| MMS | Minerals Management Service |
| MMWR | Morbidity And Mortality Weekly Report |
| MOLIS | Minority On-Line Information Service (ceased Operation 7/3/02) |
| MSA | Metropolitan Statistical Area |
| MSEL | Materials Science And Engineering Library |
| MSHA | Mine Safety And Health Administration |
| MSPB | Merit Systems Protection Board |
| NACIC | National Counterintelligence Center |
| NAFTA | North American Free Trade Agreement |
| NAICS | North American Industry Classification System |
| NAL | National Agricultural Library |
| NARA | National Archives And Records Administration |
| NARFE | National Association Of Retired Federal Employees |
| NASA | National Aeronautics And Space Administration |
| NASM | National Air And Space Museum |
| NASS | National Agricultural Statistics Service |
| NATO | North Atlantic Treaty Organisation |
| NBAC | National Bioethics Advisory Commission (replaced By PCBE; Archived At GU) |
| NBII | National Biological Information Infrastructure |
| NBL | New Brunswick Laboratory |
| NCA | National Cemetery Administration |
| NCBI | National Center For Biotechnology Information |
| NCC | National Coordinating Center For Telecommunications |
| NCCAM | National Center For Complementary And Alternative Medicine |
| NCCDPHP | National Center For Chronic Disease Prevention And Health Promotion |
| NCCIC | National Child Care Information Center |
| NCD | National Council On Disability |
| NCDC | National Climatic Data Center |
| NCEH | National Center For Environmental Health |
| NCES | National Center For Education Statistics |
| NCHS | National Center For Health Statistics |
| NCHSTP | National Center For HIV |
| NCI | National Cancer Institute |
| NCID | National Center For Infectious Diseases |
| NCIPC | National Center For Injury Prevention And Control |
| NCIS | Naval Criminal Investigative Service |
| NCJRS | National Criminal Justice Reference Service |
| NCLIS | National Commission On Libraries And Information Science |
| NCPC | National Capital Planning Commission |
| NCRR | National Center For Research Resources |
| NCS | National Communications System |
| NCTR | National Center For Toxicological Research |
| NCUA | National Credit Union Administration |
| NCVHS | National Committee On Vital And Health Statistics |
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