| Acronym | Meaning |
 | NDIC | National Drug Intelligence Center |
| NDU | National Defense University |
| NEA | National Endowment For The Arts |
| NEC | National Economic Council |
| NEGP | National Education Goals Panel (defunct) |
| NEH | National Endowment For The Humanities |
| NEI | National Eye Institute |
| NEIC | National Earthquake Information Center |
| NERSC | National Energy Research Scientific Computing Center |
| NESDIS | National Environmental Satellite |
| NETL | National Energy Technology Laboratory |
| NFA | National Fire Academy |
| NGA | National Gallery Of Art; National Geospatial-Intelligence Agency |
| NGDC | National Geophysical Data Center |
| NGS | National Geospatial Intelligence School (reorganized Into DGS And SGST) |
| NHGRI | National Human Genome Research Institute |
| NHI | National Highway Institute |
| NHIC | National Health Information Center |
| NHLBI | National Heart |
| NHPRC | National Historical Publications And Records Commission |
| NHTSA | National Highway Traffic Safety Administration |
| NIA | National Institute On Aging |
| NIAAA | National Institute On Alcohol Abuse And Alcoholism |
| NIAID | National Institute Of Allergy And Infectious Diseases |
| NIAMS | National Institute Of Arthritis And Musculoskeletal And Skin Diseases |
| NIC | National Institute Of Corrections |
| NICHD | National Institute Of Child Health And Human Development |
| NIDA | National Institute On Drug Abuse |
| NIDCD | National Institute On Deafness And Other Communication Disorders |
| NIDCR | National Institute Of Dental And Craniofacial Research |
| NIDDK | National Institute Of Diabetes And Digestive And Kidney Disease |
| NIDRR | National Institute On Disability And Rehabilitation Research |
| NIEHS | National Institute Of Environmental Health Sciences |
| NIFC | National Interagency Fire Center |
| NIFL | National Institute For Literacy |
| NIGC | National Indian Gaming Commission |
| NIGMS | National Institute Of General Medical Sciences |
| NIH | National Institutes Of Health |
| NIJ | National Institute Of Justice |
| NIMA | National Imagery And Mapping Agency (replaced By NGA) |
| NIMH | National Institute Of Mental Health |
| NINDS | National Institute Of Neurological Disorders And Stroke |
| NINR | National Institute Of Nursing Research |
| NIOSH | National Institute For Occupational Safety And Health |
| NIPA | National Income And Product Accounts |
| NIPC | National Infrastructure Protection Center |
| NIST | National Institute Of Standards And Technology |
| NISTIR | National Institute Of Standards And Technology Interagency Report |
| NLE | National Library Of Education |
| NLM | National Library Of Medicine |
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