| Acronym | Meaning |
 | DRLMS | Digital Radar Landmass Simulator |
| DRMO | Defense Reutilization & Marketing Office |
| DRRB | Data Requirements Review Board |
| DRRS | Drawing Research And Request Subsystem |
| DRS | Doppler Radar System |
| DRT | Dead Reckoning Tracer |
| DS | Defense System |
| DSARC | Defense Systems Acquisition Review Committee |
| DSB | Defense Science Board |
| DSBL | Disable |
| DSC | Digital Scan Converter |
| DSCHG | Discharge |
| DSCS III | Defense Satellite Communication System |
| DSI | Delivered Source Instruction |
| DSM | Discrete And Serial Module |
| DSMC | Defense Systems Management College |
| DSRV | Deep Submergence Rescue Vehicle (misc) |
| DSS | Data Storage Set |
| DSSA | Domain Specific Software Architecture |
| DSU | Data Synchronize Unit - Data Storage Unit |
| DSV | Deep Submergence Vehicle |
| DT | Development Testing |
| DT&E | Development Test And Evaluation |
| DTC | Data Transfer Cartridge |
| DTC | Design To Cost |
| DTD | Document Tag Description |
| DTDMA | Distributed Time Division Multiple Access |
| DTE | Data Terminal Equipment |
| DTE | Data Transfer Equipment |
| DTE | Developmental Test Equipment |
| DTIC | Defense Technical Information Center |
| DTL | Data-time Logged |
| DTR | Data Terminal Ready |
| DTR | Digital Tape Recorder |
| DTRC | David Taylor Research Center |
| DTS | Data Transfer System |
| DTU | Data Transfer Unit |
| DVS | Doppler Velocity Sensor |
| DWN | Down |
| DWNLD | Download |
| DWSMT | Defensive Weapons System Maintenance Trainer |
| DWSTT | Defensive Weapons System Team Trainer |
| E-SLCSE | Slcse Commercialization Effort |
| E2 | Exponential Elevation Display |
| E3CP | Electromagnetic Environmental Effects Control Program |
| EA | Evaluation Authority |
| EAB | Emergency Air Breathing (comm Sys For Submarines) |
| EAI | Engine Air Inlet |
| EAPS | Engine Air Particle Separator |
| EAS | Equivalent Airspeed |
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