| Acronym | Meaning |
 | OAC | Objective Assignment Chart |
| OAF | Open Architecture Framework |
| OAT | Outside Air Temperature |
| OB | Operating Budget |
| OBE | Overcome By Events |
| OBIGGS | Onboard Inert Gas Generating System |
| OBOGS | Onboard Oxygen Generating System |
| OBT | On Board Training |
| OCD | Operational Concept Document |
| OCM | On Condition Maintenance |
| OCP | Operational Computer Program |
| OCS | Officer Candidate School |
| ODA | Office Document Architecture |
| ODADS | Omnidirectional Air Data Sensor |
| ODDS | Offboard Deception Devices System |
| ODIF | Office Document Interchange Format |
| OEI | One Engine Inoperative |
| OEM | Original Equipment Manufacturer |
| OFAB | Oil Filter Actual Bypass |
| OFABL | Oil Filter Actual Bypass Left |
| OFABR | Oil Filter Actual Bypass Right |
| OFIB | Oil Filter Impending Bypass |
| OFIBL | Oil Filter Impending Bypass Left |
| OFIBR | Oil Filter Impending Bypass Right |
| OFP | Operational Flight Program |
| OFT | Operational Flight Trainer |
| OGE | Out Of Ground Effect |
| OICC | Officer In Charge Of Construction |
| OIP | Operational Improvement Program |
| OJT | On The Job Training |
| OLSP | Operational Logistic Support Plan |
| OM | Operator's Manual |
| OMA | Organizational Maintenance Activity |
| OMB | Office Of Manpower And Budget |
| OMD | Operations Maintenance Division |
| OMG | Object Management Group |
| OMNI | Vhf Omnidirectional Range |
| OMP | Organometallic Polymer Hull Coating |
| OMS | Object Management System |
| ONR | Office Of Naval Research |
| OOD | Object-oriented Design |
| OODA | Object-oriented Design With Assemblies |
| OPCON | Operational Control |
| OPER | Operator |
| OPEVAL | Operational Evaluation |
| OPI | Optional Procedure Indicator |
| OPLSM | Operational Phase Logistic Suuport Manager |
| OPN | Open |
| OPN | Other Procurement, Navy |
| OPNAV | Chief Of Naval Operations |
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