| Acronym | Meaning |
| OPS | Operational |
| OPS/CHK | Operational Checkout |
| OPTAR | Operating Target (expense) |
| OPTN | Option |
| OR | Operational Requirement |
| ORACLE | Ordnance Rapid Area Clearance |
| ORT | Operational Readiness Test |
| ORT | Operationally Ready Time |
| OS | Operating System |
| OSD | Office Of The Secretary Of Defense |
| OSF | Open Software Foundation |
| OSI | Open Systems Interconnection (iso Standard) |
| OSIP | Operational Safety & Improvement Program |
| OSMN | Operations And Maintenance-navy (funds) |
| OSQAM | Operating Standards & Quality Assurance Manual |
| OSR | On Site Representative |
| OT | Operational Test |
| OT&E | Operator Training & Evaluation |
| OTCIXS | Officer Tactical Command Information Exchange System |
| OTE | Operational Test And Evaluation |
| OTE | Operator Training Equipment |
| OTH-T | Over-the-horizon Targeting |
| OTIXS | Officer In Tactical Command Ixs |
| OTPI | On Top Position Indicator |
| OTPS | Operational Test Program Set |
| OTT | Ocean Tactical Targeting |
| OVHD | Overhead |
| OVTQ | Overtorque |
| OW | Obstacle Warning |
| OW | Operating Wing |
| OW | Outer Wing |
| OWDM | Original Water Depth Mine |
| P-P | Peak-to-peak |
| P/N | Part Number |
| P1175 | A Std Ref Model For Computing System Tool Interconnection |
| P2 | Compressor Inlet Pressure |
| P3 | Compressor Discharge Total Pressure |
| P4 | Burner Discharge Total Pressure |
| P5 | Turbine Cooling Flow Accountability Total Pressure |
| PA | Pressure Altitude |
| PA | Public Address |
| PAC | Pacific |
| PAC | Post Award Conference |
| PAC | Power Assurance Check |
| PACL | Power Assurance Check Left |
| PACR | Power Assurance Check Right |
| PAL | Process Asset Library |
| PALT | Pressure Altitude |
| PAO | Public Affairs Office(r) |
| PAPS | Propulsion Associated Parameter Set |